1084 Top startups in San Diego for January 2025

We rank Cloudbeds, StockTwits and San Diego Gas & Electric in San Diego along with 1081 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Diego ranks #24 globally and #9 in United States.

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Top Unicorn Startups in San Diego for 2025

Six startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in San Diego have raised more than USD 9.8B.
SB Score:800

ClickUp combines tasks, docs, spreadsheets, goal tracking, resources, and an inbox in one app for seamless organization. Streamline your workflow and stay productive with all your essential tools in one place.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:624

Seismic provides software solutions for global sales and marketing teams, enabling them to streamline processes and drive revenue.

Industry:
Software & Data
Subindustry:
Software

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SB Score:581

Drata automates compliance and security workflows for companies, streamlining control monitoring. With Drata, businesses can effortlessly manage security controls, ensuring they meet regulatory requirements with ease.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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Total amount:6

Best Startups in San Diego for 2025

SB Score:711

Cloudbeds offers a comprehensive software solution for hotels and accommodations to simplify operations, boost reservations, and elevate guest satisfaction.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:664

StockTwits is a dynamic platform for investors and financial professionals to share real-time insights and information about stocks. With over 300,000 members and an audience of 40 million, users can research stocks, connect with others, and stay informed about market trends all in one place.

Industry:
Social & Leisure
Subindustry:
Social Media

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SDG&E delivers dependable energy service to 3.4 million customers in San Diego and southern Orange counties, ensuring safety and reliability for all.

Industry:
Energy & Environment
Subindustry:
Energy

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4th

GovX
SB Score:600

GovX is an eCommerce platform that honors and supports the US Military and First Responder communities. Shop exclusive discounts and products catered to those who serve our country.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:591

Experience Cars & Bids, an online auction marketplace for modern enthusiast cars with daily auctions from the 1980s to the 2020s. Buy and sell your dream car with ease on this platform designed for car enthusiasts.

Industry:
Edtech
Subindustry:
Edutainment

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SB Score:581

Workiz offers an online platform for managing home service work teams, making scheduling and communication seamless. Streamline your business operations with Workiz's user-friendly interface, ensuring efficiency and organization in one convenient platform.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:573

Kandji is a cutting-edge platform for managing Apple devices like Macs, iPhones, iPads, and Apple TVs. Simplify device management with Kandji's intuitive interface and comprehensive tools for seamless control and optimization.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:568

Cortica specializes in diagnosing autism, ADHD, developmental delays, and other developmental differences. They provide a range of services, including in-home, in-clinic, and telehealth options, ensuring accessible and comprehensive support for individuals and families navigating these challenges.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:565

NetraDyne enhances fleet safety with advanced computer vision and data analysis, driving impactful improvements for businesses.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:565

Trust & Will revolutionizes estate planning with an efficient online platform for setting up your estate plan quickly, easily, and securely.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:559

Equip Health offers a virtual eating disorder treatment program for families to recover at home. Their program is designed to provide support and guidance for those struggling with eating disorders, making it easier to access help and resources from the comfort of their own home.

Industry:
Healthtech
Subindustry:
Fitness

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Total amount:1084

Top 292 Healthtech Startups in San Diego for 2025

The top three Healthtech startups in San Diego have raised more than USD 1.58B. San Diego ranks among the top 10 locations in the world for startups in Healthtech, holding the 5th position.
SB Score:568

Cortica specializes in diagnosing autism, ADHD, developmental delays, and other developmental differences. They provide a range of services, including in-home, in-clinic, and telehealth options, ensuring accessible and comprehensive support for individuals and families navigating these challenges.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:559

Equip Health offers a virtual eating disorder treatment program for families to recover at home. Their program is designed to provide support and guidance for those struggling with eating disorders, making it easier to access help and resources from the comfort of their own home.

Industry:
Healthtech
Subindustry:
Fitness

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SB Score:557

Element Biosciences develops advanced tools for genetic analysis, revolutionizing the field with cutting-edge technology. Their focus is on creating innovative solutions to empower researchers and clinicians in understanding and unlocking the secrets of the genome.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:292

Top 316 Software & Data Startups in San Diego for 2025

The top three Software & Data startups in San Diego have raised more than USD 734M. San Diego ranks #20 globally for the Software & Data industry.
SB Score:711

Cloudbeds offers a comprehensive software solution for hotels and accommodations to simplify operations, boost reservations, and elevate guest satisfaction.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:581

Workiz offers an online platform for managing home service work teams, making scheduling and communication seamless. Streamline your business operations with Workiz's user-friendly interface, ensuring efficiency and organization in one convenient platform.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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SB Score:573

Kandji is a cutting-edge platform for managing Apple devices like Macs, iPhones, iPads, and Apple TVs. Simplify device management with Kandji's intuitive interface and comprehensive tools for seamless control and optimization.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:316

Top 54 Marketing & Sales Startups in San Diego for 2025

The top three Marketing & Sales startups in San Diego have raised more than USD 120M. San Diego ranks #12 globally for the Marketing & Sales industry.
SB Score:533

Revolutionize your marketing with Intelligence Driven Marketing Automation. Track, personalize, and automate customer journey communications seamlessly. Streamline your processes and engage customers like never before.

Industry:
Marketing & Sales
Subindustry:
Adtech

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SB Score:488

Lawmatics is a comprehensive CRM and marketing automation platform tailored for modern law firms. Streamline client intake, automate marketing, and manage the entire sales process in one place.

Industry:
Marketing & Sales
Subindustry:
CRM

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SB Score:484

Revolutionize customer experiences with a tailored touch. Offering personalized solutions, this startup creates unforgettable interactions. Perfect for businesses looking to stand out in a crowded market.

Industry:
Marketing & Sales
Subindustry:
CRM

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Total amount:54

Most Funded Startups in San Diego for 2025

The top three most funded startups in San Diego have raised total funding of more than USD 1.58B. Element Biosciences has 0.41% more funding than Mirador Therapeutics.
SB Score:557

Element Biosciences develops advanced tools for genetic analysis, revolutionizing the field with cutting-edge technology. Their focus is on creating innovative solutions to empower researchers and clinicians in understanding and unlocking the secrets of the genome.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:436

Mirador Therapeutics is dedicated to advancing precision medicine for immune-mediated inflammatory and fibrotic diseases. By harnessing innovative approaches, the company aims to develop targeted therapies that improve patient outcomes and transform the treatment landscape for these challenging conditions.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:459

RayzeBio harnesses targeted radioisotopes to improve cancer outcomes, offering a powerful solution for patients.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:1084

Top Hiring Startups in San Diego by Employee Number

The top three hiring startups in San Diego have an median employee size that is between [5001-10000]
SB Score:171

Embassy of Things, located in vibrant San Diego, is spearheaded by experienced entrepreneurs specializing in industrial automation, machine learning, big data analytics, and IoT. Committed to innovation, they leverage their expertise to drive success and transform industries through cutting-edge technology solutions.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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SDG&E delivers dependable energy service to 3.4 million customers in San Diego and southern Orange counties, ensuring safety and reliability for all.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:568

Cortica specializes in diagnosing autism, ADHD, developmental delays, and other developmental differences. They provide a range of services, including in-home, in-clinic, and telehealth options, ensuring accessible and comprehensive support for individuals and families navigating these challenges.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Total amount:1084

Explore the Startup Ecosystem of San Diego

National Rank

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9th

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Regional Rank

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10th

1

Global Rank

(WorldWide)

24th

2

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Top Cities for Startups in United States - Ranked by StartupBlink
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2024 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
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1st
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710.966
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2nd
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2nd
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251.377
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3rd
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4th
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121.937
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4th
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5th
0
109.679
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00.00
00.00
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