71278 Top startups in United States for April 2025

We rank DuckDuckGo, Quora and Zillow in United States along with 71275 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. United States startup ecosystem ranks #1 globally and #1 in North America.

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Top Unicorn Startups in United States for 2025

617 startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in United States have raised more than USD 1350T.
SB Score:1000

OpenAI, an AI research and product company, enhances digital intelligence for the greater good. Their innovations, like ChatGPT, aim to improve technology for the benefit of humanity.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

City Rank (San Francisco)

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SB Score:917

Stripe is the ultimate platform for managing your online business. It streamlines all your operations, from processing payments to tracking sales, in one easy-to-use interface. Get started today and watch your internet business thrive with Stripe.

Industry:
Fintech
Subindustry:
Payments

City Rank (San Francisco)

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SB Score:908

Discord connects communities with chat, voice, and video features, perfect for gamers and interest groups. Join the fun in real-time conversations and calls on this popular communication platform.

Industry:
Software & Data
Subindustry:
Software

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Total amount:617

Best Startups in United States for 2025

SB Score:859

DuckDuckGo is a privacy-focused search engine that prioritizes user anonymity by not tracking searches or behavior. With a commitment to online privacy, it offers straightforward search services without data profiling, setting a new standard for internet privacy protection through its platform and tools.

Industry:
Software & Data
Subindustry:
Software

City Rank (Philadelphia)

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SB Score:859

Quora enables users to ask questions, share knowledge, and engage with a global community. Join to learn, connect, and contribute to a platform dedicated to expanding the world's collective wisdom.

Industry:
Software & Data
Subindustry:
Software

City Rank (Mountain View)

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SB Score:844

Zillow is an online platform that helps users find and share information about homes, real estate, and mortgages.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

City Rank (Seattle)

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SB Score:796

Brave, the privacy-focused web browser, blocks trackers and ads for a faster, safer browsing experience. Enjoy a cleaner online experience with enhanced security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

City Rank (San Francisco)

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SB Score:788

Scribd is the unlimited reading subscription that offers access to the best books, audiobooks, news and magazine articles, documents and more. Scribd's e-book subscription service is available on Android and iOS smartphones and tablets, as well as personal computers. Scribd brings together the best books, audiobooks, and journalism to help readers become their best selves. The company offers unlimited access to the best books, audiobooks, articles, documents, and more, all in one app.

Industry:
Social & Leisure
Subindustry:
Entertainment

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SB Score:768

Groupon offers discounted gift certificates for local and national businesses. Users can purchase deals for various products and services, saving money while supporting local businesses.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

City Rank (Seattle)

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SB Score:764

Athenahealth offers cloud-based business and clinical services for physician practices, including practice management, electronic health record software, payer knowledge-base, and back-office operations. Their web-native solutions streamline healthcare workflows for more efficient and effective patient care.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Watertown)

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SB Score:742

Medium is revolutionizing idea sharing by tapping into collective creativity and emphasizing the importance of design. They believe in democratizing content creation and shaping a better media landscape. Join their elite team focused on deliberate growth and innovation in engineering and design.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:738

Razer is a world leader in connected devices and software for gamers. Razer is transforming the way people play games, engage with other gamers and identify with the gamer lifestyle. Having won the coveted “Best of CES” award consecutively for six years, the company’s leadership in product innovation continues to create new categories for the gaming community that is estimated to have over 1 billion gamers worldwide. Razer’s award-winning design and technology include an array of user interface and systems devices, voice-over IP for gamers and a cloud platform for customizing and enhancing gaming devices. Founded in 2005, Razer is backed by Intel Capital, IDG-Accel and Heliconia Capital Management (Heliconia), a wholly owned subsidiary of Singapore investment company Temasek.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

City Rank (Irvine)

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SB Score:736

Healthline Networks is a provider of health information and technology solutions for publishers, advertisers, employers, healthcare providers, and health plans. Originally founded as YourDoctor.com in 1999, the company relaunched in 2005 as Healthline Networks and is organized into two business units: Healthline Media and Healthline HIT Solutions. Healthline Media, together with its flagship Healthline.com and YourDoctor.com, is one of the top ten health information destination properties according comScore. Healthline Media also manages HealthWEB—a network of health publishers that include Yahoo! Health, Drugs.com, and many others. Healthline Media is the 2nd largest and fastest growing consumer health publisher in the world, reaching 85 million people a month. You can depend on us to provide expert content along with genuine caring. We will support, guide, and inspire you toward the best possible health outcomes for you and your family. Our solid profitability and rapid growth enables us to invest in expanding our reach and offering to have even more impact on many millions more users. We have offices in San Francisco, New York City, UK, Iceland and Taiwan - and are looking for people who share our vision of a stronger, healthier world! If you're interested in careers with us, please feel free to email us at: collaborate@healthline.com

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Francisco)

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11th

x.ai
SB Score:735

X.ai is an AI-powered personal assistant that effortlessly schedules meetings for you. Say goodbye to the back-and-forth emails - X.ai streamlines the entire process, saving you time and hassle.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

City Rank (New York)

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Total amount:71263

Top 25451 Software & Data Startups in United States for 2025

The top three Software & Data startups in United States have raised more than USD 21.6B. United States startup ecosystem ranks among the top 10 locations in the world for startups in Software & Data, holding the 1st position.
SB Score:859

DuckDuckGo is a privacy-focused search engine that prioritizes user anonymity by not tracking searches or behavior. With a commitment to online privacy, it offers straightforward search services without data profiling, setting a new standard for internet privacy protection through its platform and tools.

Industry:
Software & Data
Subindustry:
Software

City Rank (Philadelphia)

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SB Score:859

Quora enables users to ask questions, share knowledge, and engage with a global community. Join to learn, connect, and contribute to a platform dedicated to expanding the world's collective wisdom.

Industry:
Software & Data
Subindustry:
Software

City Rank (Mountain View)

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SB Score:796

Brave, the privacy-focused web browser, blocks trackers and ads for a faster, safer browsing experience. Enjoy a cleaner online experience with enhanced security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

City Rank (San Francisco)

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Total amount:25451

Top 8862 Healthtech Startups in United States for 2025

The top three Healthtech startups in United States have raised more than USD 8.77B. United States startup ecosystem ranks among the top 10 locations in the world for startups in Healthtech, holding the 1st position.
SB Score:764

Athenahealth offers cloud-based business and clinical services for physician practices, including practice management, electronic health record software, payer knowledge-base, and back-office operations. Their web-native solutions streamline healthcare workflows for more efficient and effective patient care.

Industry:
Healthtech
Subindustry:
Health Care

City Rank (Watertown)

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Regional Rank (North America)

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SB Score:736

Healthline Networks is a provider of health information and technology solutions for publishers, advertisers, employers, healthcare providers, and health plans. Originally founded as YourDoctor.com in 1999, the company relaunched in 2005 as Healthline Networks and is organized into two business units: Healthline Media and Healthline HIT Solutions. Healthline Media, together with its flagship Healthline.com and YourDoctor.com, is one of the top ten health information destination properties according comScore. Healthline Media also manages HealthWEB—a network of health publishers that include Yahoo! Health, Drugs.com, and many others. Healthline Media is the 2nd largest and fastest growing consumer health publisher in the world, reaching 85 million people a month. You can depend on us to provide expert content along with genuine caring. We will support, guide, and inspire you toward the best possible health outcomes for you and your family. Our solid profitability and rapid growth enables us to invest in expanding our reach and offering to have even more impact on many millions more users. We have offices in San Francisco, New York City, UK, Iceland and Taiwan - and are looking for people who share our vision of a stronger, healthier world! If you're interested in careers with us, please feel free to email us at: collaborate@healthline.com

Industry:
Healthtech
Subindustry:
Health Care

City Rank (San Francisco)

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Memorial Sloan Kettering Cancer Center — the world’s oldest and largest private cancer center — has devoted more than 130 years to exceptional patient care, innovative research, and outstanding educational programs. Today, they are one of 41 National Cancer Institute–designated Comprehensive Cancer Centers, with state-of-the-art science flourishing side by side with clinical studies and treatment. The close collaboration between their physicians and scientists is one of their unique strengths, enabling us to provide patients with the best care available as they work to discover more-effective strategies to prevent, control, and ultimately cure cancer in the future. Their education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan Kettering has an impact on cancer treatment and biomedical research around the world.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (New York)

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Total amount:8862

Top 5736 Fintech Startups in United States for 2025

The top three Fintech startups in United States have raised more than USD 4.01B. United States startup ecosystem ranks among the top 10 locations in the world for startups in Fintech, holding the 1st position.
SB Score:687

HCentive provides innovative software solutions for health insurers and state health agencies. Their products streamline operations and improve healthcare access for millions of individuals.

Industry:
Fintech
Subindustry:
Insurance

City Rank (Reston)

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SB Score:663

Mercury offers specialized banking services and accounts tailored for startups. Simplify your financial management with their digital platform designed to meet the unique needs of new businesses.

Industry:
Fintech
Subindustry:
Online Banking

City Rank (San Francisco)

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SB Score:662

Navan provides travel, expense, and corporate card management to automate manual processes and drive spend visibility. With one of the first enterprise technologies combining the cloud, mobile, and AI to balance business requirements with current standards, the company is reinventing the legacy category of travel and expense.

Industry:
Fintech
Subindustry:
Financial Services

City Rank (Palo Alto)

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Total amount:5736

Most Funded Startups in United States for 2025

The top three most funded startups in United States have raised total funding of more than USD 66.7B. JUUL has 2.34% more funding than x.ai.

1st

JUUL
SB Score:698

JUUL produces and sells electronic nicotine vaporizers. Their sleek devices provide a convenient and discreet way for users to enjoy nicotine without the smoke and odor of traditional cigarettes.

Industry:
Social & Leisure
Subindustry:
Social & Leisure-Other

City Rank (San Francisco)

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2nd

x.ai
SB Score:735

X.ai is an AI-powered personal assistant that effortlessly schedules meetings for you. Say goodbye to the back-and-forth emails - X.ai streamlines the entire process, saving you time and hassle.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

City Rank (New York)

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SB Score:678

Waymo pioneers fully self-driving vehicles to enhance global transportation, creating safer and more efficient journeys for all.

Industry:
Transportation
Subindustry:
Automotive

City Rank (Mountain View)

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Total amount:71263

Top Hiring Startups in United States by Employee Number

The top three hiring startups in United States have an median employee size that is between [10001+]
SB Score:724

Metropolis is a cutting-edge urban mobility platform streamlining parking lot operations and offering convenient vehicle entry and payment solutions.

Industry:
Software & Data
Subindustry:
Enterprise Technology

City Rank (Los Angeles)

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SB Score:720

Micron Technology specializes in producing various semiconductor chips like DRAM, SDRAM, flash memory, SSD, and CMOS image sensors. Their products cater to a wide range of technology needs, making them a key player in the semiconductor industry.

Industry:
Hardware & IoT
Subindustry:
Hardware

City Rank (Boise)

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Regional Rank (North America)

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Memorial Sloan Kettering Cancer Center — the world’s oldest and largest private cancer center — has devoted more than 130 years to exceptional patient care, innovative research, and outstanding educational programs. Today, they are one of 41 National Cancer Institute–designated Comprehensive Cancer Centers, with state-of-the-art science flourishing side by side with clinical studies and treatment. The close collaboration between their physicians and scientists is one of their unique strengths, enabling us to provide patients with the best care available as they work to discover more-effective strategies to prevent, control, and ultimately cure cancer in the future. Their education programs train future physicians and scientists, and the knowledge and experience they gain at Memorial Sloan Kettering has an impact on cancer treatment and biomedical research around the world.

Industry:
Healthtech
Subindustry:
Biotechnology

City Rank (New York)

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SB Score:696

Enterprise Rent-A-Car is a global transportation solutions provider that offers car, truck, and motorcycle rentals as well as car sharing and car sales. Its customized rental programs are designed specifically to meet its clients’ needs. Enterprise Rent-A-Car’s mobile application allows its users to manage reservations on the go, get directions to a car rental branch, reach road side assistance 24 hours, and more. It is headquartered in Baltimore, Maryland.

Industry:
Hardware & IoT
Subindustry:
Internet of Everything

City Rank (Baltimore)

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Total amount:71278

Explore the Startup Ecosystem of United States

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335.1 Million

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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3rd
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121.937
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109.679
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