StartupBlink

9033 Top startups in San Francisco for June 2026

We rank Scribd, Brave and Cash App in San Francisco along with 9030 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Francisco startup ecosystem ranks #1 globally and #1 in United States.

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Top Unicorn Startups in San Francisco for 2026

179 startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in San Francisco have raised more than USD 289B.
SB Score:1000

OpenAI, an AI research and product company, enhances digital intelligence for the greater good. Their innovations, like ChatGPT, aim to improve technology for the benefit of humanity.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:906

Stripe is the ultimate platform for managing your online business. It streamlines all your operations, from processing payments to tracking sales, in one easy-to-use interface. Get started today and watch your internet business thrive with Stripe.

Industry:
Fintech
Subindustry:
Payments

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SB Score:877

Discord connects communities with chat, voice, and video features, perfect for gamers and interest groups. Join the fun in real-time conversations and calls on this popular communication platform.

Industry:
Software & Data
Subindustry:
Software

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Total amount:179

Best Startups in San Francisco for 2026

SB Score:787

Scribd is the unlimited reading subscription that offers access to the best books, audiobooks, news and magazine articles, documents and more. Scribd's e-book subscription service is available on Android and iOS smartphones and tablets, as well as personal computers. Scribd brings together the best books, audiobooks, and journalism to help readers become their best selves. The company offers unlimited access to the best books, audiobooks, articles, documents, and more, all in one app.

Industry:
Social & Leisure
Subindustry:
Entertainment

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SB Score:782

Brave, the privacy-focused web browser, blocks trackers and ads for a faster, safer browsing experience. Enjoy a cleaner online experience with enhanced security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:735

Cash App is a rapidly expanding financial platform that enables users to send and receive money instantly, invest in stocks, and buy Bitcoin. With its user-friendly interface and innovative features, Cash App simplifies personal finance, making it accessible and convenient for everyone.

Industry:
Fintech
Subindustry:
Financial Services

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4th

Deel
SB Score:717

Deel is a comprehensive global compliance and payroll solution that empowers businesses to hire talent from anywhere in the world. Its innovative technology streamlines payroll, HR, compliance, and benefits, enabling companies to efficiently manage their international teams and ensure seamless operations across borders.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:715

Narvar is a customer experience platform that helps retailers inspire long-term customer loyalty, at all steps of the post-purchase journey. It helps retailers inspire loyalty beyond reason. As an enterprise-grade customer experience platform serving 500+ retailers like Sephora, Patagonia, Home Depot, Gap, and Bose, Narvar enables seamless post-purchase experiences that retain, engage, and delight customers — from cart to doorstep, and beyond. With effortless order tracking, proactive communications, and seamless returns, Narvar applies machine learning across billions of interactions to simplify the everyday lives of consumers. The company was established in 2012 and is based in San Francisco, California.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:696

Healthline Networks is a provider of health information and technology solutions for publishers, advertisers, employers, healthcare providers, and health plans. Originally founded as YourDoctor.com in 1999, the company relaunched in 2005 as Healthline Networks and is organized into two business units: Healthline Media and Healthline HIT Solutions. Healthline Media, together with its flagship Healthline.com and YourDoctor.com, is one of the top ten health information destination properties according comScore. Healthline Media also manages HealthWEB—a network of health publishers that include Yahoo! Health, Drugs.com, and many others. Healthline Media is the 2nd largest and fastest growing consumer health publisher in the world, reaching 85 million people a month. You can depend on us to provide expert content along with genuine caring. We will support, guide, and inspire you toward the best possible health outcomes for you and your family. Our solid profitability and rapid growth enables us to invest in expanding our reach and offering to have even more impact on many millions more users. We have offices in San Francisco, New York City, UK, Iceland and Taiwan - and are looking for people who share our vision of a stronger, healthier world! If you're interested in careers with us, please feel free to email us at: collaborate@healthline.com

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:689

Change.org is the world’s largest social change platform with over 150 million users in 196 countries. Change.org empowers anyone, anywhere, to create the change they want to see. On Change.org, people everywhere are starting campaigns, mobilizing supporters, and working with decision-makers to drive solutions. Change.org is a certified B-corporation, a new class of companies dedicated to positive impact. Investors include Bill Gates, Arianna Huffington, Ev Williams, Richard Branson, Reid Hoffman, and the Omidyar Network, started by eBay founder Pierre Omidyar.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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8th

JUUL
SB Score:675

JUUL produces and sells electronic nicotine vaporizers. Their sleek devices provide a convenient and discreet way for users to enjoy nicotine without the smoke and odor of traditional cigarettes.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:675

RealPage develops on-demand multifamily property management software for the apartment communities in the United States. Its on-demand product lines include OneSite property management systems, which include payment processing, central reporting, and document management systems for automating the leasing, renting, purchasing, facilities management, and accounting of housing properties. CrossFire sales and marketing systems that capture and manage leads for enabling residents to report maintenance needs for enhancing occupancy and build retention; and YieldStar asset optimization systems that provide statistical support for site development, market position analysis, micro and macro supply and demand forecasting, and revenue optimization. The company also provides Velocity utility and billing service, which include resident billing, utility invoice processing, and sub metering services; LeasingDesk point of lease systems that streamline the online leasing process; StarFire entertainment and communication services that create Internet protocol-connected communities; and Central Reporting, a data platform that consolidates data from property management operations with marketing, accounting, and financial back-office systems. The company, formerly known as RealPage Communications, Inc., was founded in 1995 and is headquartered in Carrollton, Texas.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

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10th

Motive
SB Score:674

Motive develops technology that connects and automates physical operations for businesses across various industries. The company provides a platform that combines telematics, fleet management, compliance tools, equipment monitoring, and AI-powered safety solutions. Its products help companies track vehicles, monitor driver behavior, automate workflows, and ensure regulatory compliance through real-time data and analytics. Motive also offers integrated solutions for spend management and maintenance, enabling businesses to control costs and improve operational efficiency. The platform supports diverse sectors including trucking, construction, oil and gas, and agriculture by centralizing data and enabling actionable insights. Through automation and visibility, Motive helps organizations optimize asset utilization and enhance decision-making in day-to-day operations.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:668

UserTesting offers a platform for receiving immediate feedback on websites, apps, and products from specific users globally. Get real-time insights to improve user experience and product performance.

Industry:
Marketing & Sales
Subindustry:
Data Analytics

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Total amount:9034

SB Score:782

Brave, the privacy-focused web browser, blocks trackers and ads for a faster, safer browsing experience. Enjoy a cleaner online experience with enhanced security.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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2nd

Deel
SB Score:717

Deel is a comprehensive global compliance and payroll solution that empowers businesses to hire talent from anywhere in the world. Its innovative technology streamlines payroll, HR, compliance, and benefits, enabling companies to efficiently manage their international teams and ensure seamless operations across borders.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:689

Change.org is the world’s largest social change platform with over 150 million users in 196 countries. Change.org empowers anyone, anywhere, to create the change they want to see. On Change.org, people everywhere are starting campaigns, mobilizing supporters, and working with decision-makers to drive solutions. Change.org is a certified B-corporation, a new class of companies dedicated to positive impact. Investors include Bill Gates, Arianna Huffington, Ev Williams, Richard Branson, Reid Hoffman, and the Omidyar Network, started by eBay founder Pierre Omidyar.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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Total amount:4575

SB Score:696

Healthline Networks is a provider of health information and technology solutions for publishers, advertisers, employers, healthcare providers, and health plans. Originally founded as YourDoctor.com in 1999, the company relaunched in 2005 as Healthline Networks and is organized into two business units: Healthline Media and Healthline HIT Solutions. Healthline Media, together with its flagship Healthline.com and YourDoctor.com, is one of the top ten health information destination properties according comScore. Healthline Media also manages HealthWEB—a network of health publishers that include Yahoo! Health, Drugs.com, and many others. Healthline Media is the 2nd largest and fastest growing consumer health publisher in the world, reaching 85 million people a month. You can depend on us to provide expert content along with genuine caring. We will support, guide, and inspire you toward the best possible health outcomes for you and your family. Our solid profitability and rapid growth enables us to invest in expanding our reach and offering to have even more impact on many millions more users. We have offices in San Francisco, New York City, UK, Iceland and Taiwan - and are looking for people who share our vision of a stronger, healthier world! If you're interested in careers with us, please feel free to email us at: collaborate@healthline.com

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:653

Doximity is a digital platform for medical professionals. The company’s network members include over 70% of U.S. physicians across all specialties and practice areas. Doximity provides its verified clinical membership with digital tools built for medicine, enabling them to collaborate with colleagues, stay up to date with the latest medical news and research, manage their careers, and conduct virtual patient visits. Doximity’s mission is to help doctors be more productive so they can provide better healthcare for their patients.

Industry:
Healthtech
Subindustry:
Health Care

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3rd

Eaze
SB Score:608

Eaze is an online marketplace and technology platform that helps provide legal access to cannabis through safe and convenient delivery. In doing so, Eaze works with and assists local cannabis entrepreneurs in expanding their businesses sustainably and responsibly.

Industry:
Healthtech
Subindustry:
Cannabis

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Total amount:644

SB Score:735

Cash App is a rapidly expanding financial platform that enables users to send and receive money instantly, invest in stocks, and buy Bitcoin. With its user-friendly interface and innovative features, Cash App simplifies personal finance, making it accessible and convenient for everyone.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:653

Mission Lane is a fintech company that provides access to financial tools, including debit and credit options. They offer digital tools designed to help customers improve their credit scores. Additionally, Mission Lane utilizes data analytics and machine learning to assist customers in rebuilding their financial lives.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:649

PayJoy's mission is to deliver access to credit to the next billion people in emerging markets worldwide. Our unique mobile security technology gives customers the ability to afford their first smartphone on credit, using the phone itself as collateral, and then provides further access to credit to help weather life's unexpected financial surprises and climb the ladder of economic well-being. Founded in 2015, today PayJoy has reached over 10 million of customers in emerging markets around the globe, including Mexico, Brazil, Colombia, Ecuador, Panama, Peru, and South Africa, and is solidly profitable and growing.

Industry:
Fintech
Subindustry:
Financial Services

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Total amount:928

Most Funded Startups in San Francisco for 2026

The top three most funded startups in San Francisco have raised total funding of more than USD 19.9B. JUUL has 3.98% more funding than Altos Labs.

1st

JUUL
SB Score:675

JUUL produces and sells electronic nicotine vaporizers. Their sleek devices provide a convenient and discreet way for users to enjoy nicotine without the smoke and odor of traditional cigarettes.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:540

Altos Labs is a biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine. The company comprises a community of leading scientists, clinicians, and leaders from both academia and industry working together towards this common mission. Altos has operations in the San Francisco Bay Area and San Diego, and in Cambridge, UK, with significant collaborations in Japan.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:598

Zipline is a California-based automated logistics company that designs, manufactures, and operates drones to deliver vital medical products. Zipline's mission is to provide every human on Earth with instant access to vital medical supplies. In 2014, Zipline was created to deliver medicine to those who needed it. Since then, the company has built a quick delivery drone and an autonomous logistics network. Zipline designs and tests its technology in Half Moon Bay, California. The company assembles the drones and the technology that powers their distribution.

Industry:
Hardware & IoT
Subindustry:
Hardware

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Total amount:9034

Top Hiring Startups in San Francisco by Employee Number

The top three hiring startups in San Francisco have an median employee size that is between [10001+]
SB Score:478

Taekus is a fintech company that provides credit card benefits to travelers. The Taekus credit card optimizes points, starting with airline tickets. Now, anyone can get 10x more value out of their premium credit card rewards — without spending hours analyzing the fine print. The company was founded in 2020 and is based iun San Francisco, California.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:439

Handshake is a decentralized, permissionless naming protocol compatible. By using Handshake, one can participate in a decentralized open naming platform secured by a decentralized peer-to-peer network.

Industry:
Software & Data
Subindustry:
SaaS

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SB Score:425

Cloud Software Group empowers modern enterprises to adapt, transform, and overcome challenges in private, public, and managed sectors.

Industry:
Software & Data
Subindustry:
Web Development

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SB Score:415

HumanFirst accelerates the adoption of patient-centered clinical trials using precision digital measures (e.g., digital biomarkers and eCOA). At HumanFirst, we offer a precision measures platform - the world’s largest AI-powered SaaS platform trusted to improve human outcomes. We provide insights, intelligence, and accuracy with validated evidence data to precisely guide and accelerate human-centric drug development. Twenty-two of the 25 largest pharmaceutical companies in the world have used the HumanFirst platform to evaluate and enable the deployment of digital health technologies (DHTs).

Industry:
Healthtech
Subindustry:
Health Care

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Total amount:9033

Explore the Startup Ecosystem of San Francisco

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
2026 National Rank CityGlobal RankTotal ScoreAnnual Growth

Access subscores for 1000 cities and 100 countries

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Quality ScoreBusiness Score
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