351 Top startups in San Mateo for January 2025

We rank PingPong, Swing Education and Sleeper in San Mateo along with 348 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. San Mateo is part of San Francisco Bay which ranks #1 globally and #1 in North America.

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Top Unicorn Startups in San Mateo for 2025

Ten startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in San Mateo have raised more than USD 13.7B.
SB Score:709

Verkada's user-friendly software platform, Command, simplifies camera and site management across all devices. Effortlessly monitor and control cameras with intuitive features for seamless operation.

Industry:
Software & Data
Subindustry:
Education-Other

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SB Score:649

Neo4j is the leading graph data platform, empowering organizations like Comcast, ICIJ, NASA, UBS, and Volvo Cars to harness real-world context in their data for solving challenges of all sizes.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:616

Guideline provides hassle-free retirement benefits, handling payroll integration, employee onboarding, and plan administration. With over 40 low-cost investment options, participants can easily choose their preferred mutual funds. Enjoy great retirement benefits without the heavy lifting.

Industry:
Fintech
Subindustry:
Fintech-Other

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Total amount:10

Best Startups in San Mateo for 2025

SB Score:663

Revolutionizing global eCommerce, this unique Fintech startup is dedicated to empowering marketplace sellers worldwide. Their focus on international markets sets them apart, making them the go-to choice for sellers looking to streamline their financial transactions and grow their businesses on a global scale.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:618

Swing Education connects schools with substitute teachers to cover difficult staff absences. Streamlining the process, Swing Education ensures a seamless experience for both educators and schools.

Industry:
Edtech
Subindustry:
Edtech

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SB Score:616

Sleeper is a dynamic sports platform for fantasy leagues and eSports. Engage with fantasy teams and eSports competitions in one place. Get ready to experience the ultimate sports gaming experience all in one convenient app.

Industry:
Social & Leisure
Subindustry:
Sports

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SB Score:604

Yellow.ai empowers enterprises with a customer experience automation platform that uses advanced NLP technology to create chat and voice bots. Streamlining communication and enhancing customer interactions, Yellow.ai helps businesses improve efficiency and provide seamless support.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:604

OneSignal is a platform for businesses to engage with customers through targeted messaging. It helps create meaningful connections and improve customer relationships.

Industry:
Software & Data
Subindustry:
Web Development

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SB Score:592

Galxe is the world's leading Web3 credential data network, providing a collaborative infrastructure for brands and developers to engage communities and create innovative products in the Web3 space. Formerly known as Project Galaxy, it empowers users to leverage credential data effectively.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:584

Cyence offers a groundbreaking platform that calculates cyber risks in probabilities and dollars, revolutionizing how businesses assess and manage their cybersecurity strategies.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:573

Engageli is a user-friendly digital learning platform that promotes inclusivity. It provides an engaging online environment for all learners.

Industry:
Edtech
Subindustry:
Edtech

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SB Score:570

Cyera offers cloud data security solutions for organizations, providing a clear picture of data reality. Founded in 2021 and based in San Mateo, USA, Cyera helps companies protect their data with confidence.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:568

Workona provides a cloud-based work management platform that empowers users to efficiently access and manage resources. With features like customizable workspace tabs, tab management, tab suspension, and document templates, it streamlines workflows and enhances productivity for individuals and teams alike.

Industry:
Software & Data
Subindustry:
SaaS

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11th

Alpaca
SB Score:560

Alpaca creates a modern financial service platform catering to tech-savvy users. Their startup offers a seamless and innovative approach to managing finances for the new generation, providing a user-friendly experience.

Industry:
Fintech
Subindustry:
Fintech-Other

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Total amount:351

Top 182 Software & Data Startups in San Mateo for 2025

The top three Software & Data startups in San Mateo have raised more than USD 1.5B. San Mateo is part of San Francisco Bay which ranks #1 globally for the Software & Data industry.
SB Score:604

Yellow.ai empowers enterprises with a customer experience automation platform that uses advanced NLP technology to create chat and voice bots. Streamlining communication and enhancing customer interactions, Yellow.ai helps businesses improve efficiency and provide seamless support.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:604

OneSignal is a platform for businesses to engage with customers through targeted messaging. It helps create meaningful connections and improve customer relationships.

Industry:
Software & Data
Subindustry:
Web Development

National Rank (United States)

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SB Score:592

Galxe is the world's leading Web3 credential data network, providing a collaborative infrastructure for brands and developers to engage communities and create innovative products in the Web3 space. Formerly known as Project Galaxy, it empowers users to leverage credential data effectively.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:182

Top 31 Fintech Startups in San Mateo for 2025

The top three Fintech startups in San Mateo have raised more than USD 326M. San Mateo is part of San Francisco Bay which ranks #1 globally for the Fintech industry.
SB Score:663

Revolutionizing global eCommerce, this unique Fintech startup is dedicated to empowering marketplace sellers worldwide. Their focus on international markets sets them apart, making them the go-to choice for sellers looking to streamline their financial transactions and grow their businesses on a global scale.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:560

Alpaca creates a modern financial service platform catering to tech-savvy users. Their startup offers a seamless and innovative approach to managing finances for the new generation, providing a user-friendly experience.

Industry:
Fintech
Subindustry:
Fintech-Other

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SB Score:467

Second Measure uses credit card transaction data to provide real-time insights into consumer behavior, helping businesses make informed decisions.

Industry:
Fintech
Subindustry:
Fintech-Other

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Total amount:31

Top 32 Healthtech Startups in San Mateo for 2025

The top three Healthtech startups in San Mateo have raised more than USD 777M. San Mateo is part of San Francisco Bay which ranks #1 globally for the Healthtech industry.

1st

Bold
SB Score:454

Bold is a digital fitness program tailored for older adults, empowering them to achieve their strongest, happiest, and healthiest lives from the comfort of home. By offering engaging workouts and wellness resources, Bold supports users in enhancing their overall well-being and vitality.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:439

Greenrush is an online marketplace connecting consumers with cannabis dispensaries. Find your perfect match and shop for all your cannabis needs in one convenient platform.

Industry:
Healthtech
Subindustry:
Cannabis

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SB Score:420

MORE Health connects users to top physicians globally through its online medical collaboration platform, providing unparalleled access to expert healthcare.

Industry:
Healthtech
Subindustry:
Health Care

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Total amount:32

Most Funded Startups in San Mateo for 2025

The top three most funded startups in San Mateo have raised total funding of more than USD 1.75B. Cyera has 0.31% more funding than Veev.
SB Score:570

Cyera offers cloud data security solutions for organizations, providing a clear picture of data reality. Founded in 2021 and based in San Mateo, USA, Cyera helps companies protect their data with confidence.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

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2nd

Veev
SB Score:543

Veev revolutionizes home construction and living with innovative solutions. Experience a new way of building and enjoying homes with Veev's hybrid real estate approach.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

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SB Score:549

Helix integrates genomics data into clinical care, advancing research and personalized health solutions.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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Total amount:351

Top Hiring Startups in San Mateo by Employee Number

The top three hiring startups in San Mateo have an median employee size that is between [1001-5000]
SB Score:584

Cyence offers a groundbreaking platform that calculates cyber risks in probabilities and dollars, revolutionizing how businesses assess and manage their cybersecurity strategies.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

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SB Score:663

Revolutionizing global eCommerce, this unique Fintech startup is dedicated to empowering marketplace sellers worldwide. Their focus on international markets sets them apart, making them the go-to choice for sellers looking to streamline their financial transactions and grow their businesses on a global scale.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (United States)

0

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SB Score:453

Apttus Intelligent Cloud streamlines Quote-to-Cash operations for global enterprises with AI-powered recommendations and intuitive interfaces. Enhance your sales channels with the best cloud infrastructure and purpose-built platform for maximum efficiency and effectiveness.

Industry:
Software & Data
Subindustry:
SaaS

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Total amount:351

Explore the Startup Ecosystem of San Mateo

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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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3rd
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4th
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121.937
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5th
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109.679
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