Top Unicorn Startups in San Mateo for 2025

In San Mateo, we rank 9 unicorn startups based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Unicorns in San Mateo are falling behind the performance of their global counterparts.

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Top Unicorn Startups in San Mateo for 2025

SB Score:661

Verkada's user-friendly software platform, Command, simplifies camera and site management across all devices. Effortlessly monitor and control cameras with intuitive features for seamless operation.

Industry:
Software & Data
Subindustry:
Education-Other

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SB Score:606

Evidation measures health in everyday life and enables anyone to participate in groundbreaking research and health programs. Built upon a foundation of user privacy and control over permissioned health data, Evidation's Achievement platform is trusted by millions of individuals—generating data with unprecedented speed, scale, and rigor. We partner with leading healthcare companies to understand health and disease outside the clinic walls. Guided by our mission to enable and empower everyone to participate in better health outcomes, Evidation is working to bring people individualized, proactive, and accessible healthcare—faster. Founded in 2012, Evidation Heath is headquartered in California. We collaborate as a distributed team with additional offices around the globe. To learn more, visit evidation.com, or follow us on Twitter @evidation

Industry:
Software & Data
Subindustry:
Apps

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SB Score:600

Neo4j is the leading graph data platform, empowering organizations like Comcast, ICIJ, NASA, UBS, and Volvo Cars to harness real-world context in their data for solving challenges of all sizes.

Industry:
Software & Data
Subindustry:
Data Analytics

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Total amount:9

Best Software & Data Startups in San Mateo for 2025

San Mateo startups in the Software & Data industry are overperforming their global industry peers. The top three Software & Data unicorns in San Mateo have raised more than USD 1.81B, an amount that is higher than the global industry average.
SB Score:661

Verkada's user-friendly software platform, Command, simplifies camera and site management across all devices. Effortlessly monitor and control cameras with intuitive features for seamless operation.

Industry:
Software & Data
Subindustry:
Education-Other

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:606

Evidation measures health in everyday life and enables anyone to participate in groundbreaking research and health programs. Built upon a foundation of user privacy and control over permissioned health data, Evidation's Achievement platform is trusted by millions of individuals—generating data with unprecedented speed, scale, and rigor. We partner with leading healthcare companies to understand health and disease outside the clinic walls. Guided by our mission to enable and empower everyone to participate in better health outcomes, Evidation is working to bring people individualized, proactive, and accessible healthcare—faster. Founded in 2012, Evidation Heath is headquartered in California. We collaborate as a distributed team with additional offices around the globe. To learn more, visit evidation.com, or follow us on Twitter @evidation

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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Regional Rank (North America)

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SB Score:600

Neo4j is the leading graph data platform, empowering organizations like Comcast, ICIJ, NASA, UBS, and Volvo Cars to harness real-world context in their data for solving challenges of all sizes.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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Total amount:5

Most Valuable Unicorns in San Mateo for 2025

The top three most valuable unicorns in San Mateo have raised total funding of more than USD 1.82B. Among the top three funded unicorns, the most popular industry, based on total funding, is Software & Data.
SB Score:530

FalconX is a cryptocurrency brokerage and digital asset trading platform. It specializes in the fields of blockchain, cryptocurrency, and fintech. Its platform provides reliable execution using data science to eliminate slippage and hidden fees. It was founded in 2018 and is based in San Mateo, California.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (United States)

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SB Score:661

Verkada's user-friendly software platform, Command, simplifies camera and site management across all devices. Effortlessly monitor and control cameras with intuitive features for seamless operation.

Industry:
Software & Data
Subindustry:
Education-Other

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SB Score:498

SiFive designs chips for the semiconductor industry. It offers the system on a chip for the microcontroller, embedded, IoT, and wearable applications, and toolset to provide debug capabilities. SiFive brings the power of open source and software automation to the semiconductor industry, making it possible to develop new hardware faster and more affordably than ever before. With the platform for designing, testing, and building RISC‑V-based core IP and chips, they’re accelerating the pace of innovation for businesses large and small.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

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Total amount:9

Top Hiring Unicorns in San Mateo by Employee Number

The top three hiring unicorns in San Mateo have an average employee size that is larger than to the global average. Among these, the Software & Data industry features the unicorn with the largest workforce.
SB Score:661

Verkada's user-friendly software platform, Command, simplifies camera and site management across all devices. Effortlessly monitor and control cameras with intuitive features for seamless operation.

Industry:
Software & Data
Subindustry:
Education-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:600

Neo4j is the leading graph data platform, empowering organizations like Comcast, ICIJ, NASA, UBS, and Volvo Cars to harness real-world context in their data for solving challenges of all sizes.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

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SB Score:550

Truepill offers a game-changing healthcare experience through its API-connected infrastructure. Revolutionize patient care with seamless technology integration.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

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SB Score:498

SiFive designs chips for the semiconductor industry. It offers the system on a chip for the microcontroller, embedded, IoT, and wearable applications, and toolset to provide debug capabilities. SiFive brings the power of open source and software automation to the semiconductor industry, making it possible to develop new hardware faster and more affordably than ever before. With the platform for designing, testing, and building RISC‑V-based core IP and chips, they’re accelerating the pace of innovation for businesses large and small.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:9

Explore the Startup Ecosystem of San Mateo

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
-
1
37.971
00.00
00.00
00.00
9th
0
24th
-
2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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