46 Top startups in Syracuse for January 2025

We rank Hidden Level, PLOWZ & MOWZ and Quadrant Biosciences in Syracuse along with 43 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Syracuse ranks #262 globally and #76 in United States.

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Exits

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Accelerators

Top Unicorn Startups in Syracuse for 2025

Density is the only unicorn in Syracuse raising more than USD 1.05B. It is the undefined ranked unicorn in North America.
SB Score:469

Density is a compact device that counts people in a room by detecting smartphone WiFi or MAC addresses. It provides data on visitor count, duration, and loyalty. With a native app for iOS, it offers analytics for local businesses. Its network can identify referral traffic and similarities between businesses.

Industry:
Software & Data
Subindustry:
Apps

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Total amount:1

Best Startups in Syracuse for 2025

SB Score:371

Hidden Level specializes in radar sensors, engineering contracting, and digital signal processing for the aviation and aerospace industries. Their expertise lies in cutting-edge technology solutions for enhanced performance and efficiency.

Industry:
Hardware & IoT
Subindustry:
Hardware & IoT-Other

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SB Score:341

PLOWZ & MOWZ is the go-to app for convenient residential snow removal and lawn care services. With just a few taps on your smartphone, users can easily schedule and manage their outdoor maintenance needs.

Industry:
Software & Data
Subindustry:
Software

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SB Score:316

Quadrant Biosciences specializes in developing, testing, and distributing innovative products. With expertise in engineering, production, marketing, and sales, they create cutting-edge solutions for various industries.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:312

ZetaGen Therapeutics is pioneering a small molecule-based osteoinductive platform that activates a unique molecular pathway to develop innovative bone growth products. The company aims to combat cancer, alleviate pain, and promote bone regeneration, transforming the landscape of orthopedic and oncological treatments.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:290

Repair Biotechnologies is a biotech company focused on developing and delivering cutting-edge therapies to the clinic. Their goal is to revolutionize healthcare through advanced biotechnological solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:282

TruWeather offers a reliable solution to help weather-sensitive businesses recover lost profits. With a proven framework, they specialize in maximizing revenue potential during unpredictable weather conditions.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SelectFI utilizes its innovative Predictive Lending™ analysis to prequalify customers for financing, seamlessly connecting them with an auto dealership's existing lenders. This streamlined approach enhances the car-buying experience, making it easier for customers to secure financing tailored to their needs.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (United States)

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SB Score:276

StorySlab is a user-friendly tablet sales system that enhances sales pitches, expands marketing efforts, and meets IT standards.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:274

Kamkalima leverages innovative educational technology to empower students in honing their Arabic communication skills. By providing interactive tools and engaging content, it fosters a dynamic learning environment that enhances both fluency and confidence in speaking Arabic.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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SB Score:274

Revolutionize construction with a cutting-edge Mixed Reality Solution. Seamlessly blend virtual and physical worlds to enhance project visualization, collaboration, and efficiency. Experience a new level of innovation in the construction industry.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:269

BioNeex is a cutting-edge platform connecting biotech and biopharmaceutical companies for R&D collaboration. Join this open exchange marketplace to streamline innovation in the biopharma industry.

Industry:
Ecommerce & Retail
Subindustry:
Retail

National Rank (United States)

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Regional Rank (North America)

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Total amount:46

Top 11 Software & Data Startups in Syracuse for 2025

The top three Software & Data startups in Syracuse have raised more than USD 16.1M. Syracuse ranks #174 globally for the Software & Data industry.
SB Score:341

PLOWZ & MOWZ is the go-to app for convenient residential snow removal and lawn care services. With just a few taps on your smartphone, users can easily schedule and manage their outdoor maintenance needs.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:282

TruWeather offers a reliable solution to help weather-sensitive businesses recover lost profits. With a proven framework, they specialize in maximizing revenue potential during unpredictable weather conditions.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:276

StorySlab is a user-friendly tablet sales system that enhances sales pitches, expands marketing efforts, and meets IT standards.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:11

Top 4 Hardware & IoT Startups in Syracuse for 2025

The top three Hardware & IoT startups in Syracuse have raised more than USD 34.4M. Syracuse ranks #221 globally for the Hardware & IoT industry.
SB Score:371

Hidden Level specializes in radar sensors, engineering contracting, and digital signal processing for the aviation and aerospace industries. Their expertise lies in cutting-edge technology solutions for enhanced performance and efficiency.

Industry:
Hardware & IoT
Subindustry:
Hardware & IoT-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:274

Revolutionize construction with a cutting-edge Mixed Reality Solution. Seamlessly blend virtual and physical worlds to enhance project visualization, collaboration, and efficiency. Experience a new level of innovation in the construction industry.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:185

3D Usher is an online platform that connects users with low-volume manufacturers, designers, and post-processing units, enabling seamless on-demand manufacturing. By simply submitting a few details, users can easily have their parts produced without needing specialized skills or infrastructure.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:4

Top 8 Healthtech Startups in Syracuse for 2025

The top three Healthtech startups in Syracuse have raised more than USD 35.4M. Syracuse ranks #314 globally for the Healthtech industry.
SB Score:316

Quadrant Biosciences specializes in developing, testing, and distributing innovative products. With expertise in engineering, production, marketing, and sales, they create cutting-edge solutions for various industries.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:312

ZetaGen Therapeutics is pioneering a small molecule-based osteoinductive platform that activates a unique molecular pathway to develop innovative bone growth products. The company aims to combat cancer, alleviate pain, and promote bone regeneration, transforming the landscape of orthopedic and oncological treatments.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:290

Repair Biotechnologies is a biotech company focused on developing and delivering cutting-edge therapies to the clinic. Their goal is to revolutionize healthcare through advanced biotechnological solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:8

Most Funded Startups in Syracuse for 2025

The top three most funded startups in Syracuse have raised total funding of more than USD 56.3M. Hidden Level has 1.15% more funding than ZetaGen Therapeutics.
SB Score:371

Hidden Level specializes in radar sensors, engineering contracting, and digital signal processing for the aviation and aerospace industries. Their expertise lies in cutting-edge technology solutions for enhanced performance and efficiency.

Industry:
Hardware & IoT
Subindustry:
Hardware & IoT-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:312

ZetaGen Therapeutics is pioneering a small molecule-based osteoinductive platform that activates a unique molecular pathway to develop innovative bone growth products. The company aims to combat cancer, alleviate pain, and promote bone regeneration, transforming the landscape of orthopedic and oncological treatments.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:290

Repair Biotechnologies is a biotech company focused on developing and delivering cutting-edge therapies to the clinic. Their goal is to revolutionize healthcare through advanced biotechnological solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:46

Top Hiring Startups in Syracuse by Employee Number

The top three hiring startups in Syracuse have an median employee size that is between [51-100]

Sorensen Companies is a telecommunications provider specializing in utility excavation and telecom infrastructure solutions, delivering innovative services that enhance connectivity and streamline operations. Their expertise supports the development of robust networks, ensuring reliable communication and efficient utility management for clients in various sectors.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:371

Hidden Level specializes in radar sensors, engineering contracting, and digital signal processing for the aviation and aerospace industries. Their expertise lies in cutting-edge technology solutions for enhanced performance and efficiency.

Industry:
Hardware & IoT
Subindustry:
Hardware & IoT-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:316

Quadrant Biosciences specializes in developing, testing, and distributing innovative products. With expertise in engineering, production, marketing, and sales, they create cutting-edge solutions for various industries.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:341

PLOWZ & MOWZ is the go-to app for convenient residential snow removal and lawn care services. With just a few taps on your smartphone, users can easily schedule and manage their outdoor maintenance needs.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:46

Explore the Startup Ecosystem of Syracuse

National Rank

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76th

9

Regional Rank

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88th

10

Global Rank

(WorldWide)

262nd

35

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Top Cities for Startups in United States - Ranked by StartupBlink
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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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109.679
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