20 Top startups in State College for April 2025

We rank kdanmobile, Phospholutions and NeuExcell Therapeutics in State College along with 17 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. State College startup ecosystem ranks #552 globally and #157 in United States.

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Best Startups in State College for 2025

SB Score:351

We sell Mobile Apps for schools, enterprises and design/photography. Our products include: The Kdan Cloud, Software Development Kits, Animation Desk, Pocket Snapper, Pdf Connoisseur, Note ledge and many more.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:320

Phospholutions, a State College, PA startup, offers sustainable fertilizers. Their innovative products help improve crop growth while minimizing environmental impact.

Industry:
Foodtech
Subindustry:
Agtech

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SB Score:313

NeuExcell is an early stage gene therapy company focusing on neurodegenerative diseases. We have developed a disruptive neural repair technology that utilizes in vivo astrocyte-to-neuron conversion. Our vision is to improve the quality of life of millions of patients worldwide who are suffering from neurodegenerative conditions by using the power of gene therapy to restore damaged neural tissue.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:310

Analytical Flavor Systems’ AI-driven Gastrograph platform helps packaged food companies achieve greater success in a saturated food industry that has an over 80% failure rate. Gastograph moves CPG brands’ development process beyond traditional tasting panels, it surveys each product with a flavor profile engine that is predictive, anticipating how new foods will perform in different markets, over a long time horizon, and against various demographic archetypes. Food companies are struggling to launch new products in an era of rapidly shifting consumer tastes, and an AI-driven platform like Gastrograph gives big food a more accurate map with which to navigate into the future.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Regional Rank (North America)

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SB Score:295

spotLESS Materials is driven by a dedicated research team of experts in materials, mechanical, and bio-inspired engineering. They actively tackle global challenges and commercial opportunities through innovative research projects, creating advanced solutions that address pressing needs in various industries.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

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Regional Rank (North America)

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SB Score:284

Videon develops products for audio/video applications in the Global AV, Aviation, and Automotive industries. With over 30 million devices using its streaming media, DVD, and Blu-ray technology, Videon is a partner to the world technology companies and AV product developers. Its holistic approach supports customers at any stage in product development, offering expertise during ideation, design, development, manufacturing, certification, and support. All of these are done in-house, simplifying, and streamlining the process. Since its founding, Videon has achieved a number of industry firsts, including the first universal Blu-ray Disc and HD DVD player and the first optical disc Google TV. Our Android app Avia was one of the first apps to be released with support for Google Chromecast, and for weeks Avia was the most popular Android app. It’s been downloaded over a million times. Videon continues to grow and expand into new industries, and we have made the Inc. 5000 list of America’s fastest-growing private companies four times.

Industry:
Social & Leisure
Subindustry:
Entertainment

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Regional Rank (North America)

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SB Score:221

Aleo BME, Inc. is a biotechnology R&D company based in State College, Pennsylvania, dedicated to advancing innovative solutions in healthcare. By leveraging cutting-edge research and technology, Aleo BME aims to transform scientific discoveries into impactful therapies that improve patient outcomes and enhance quality of life.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:189

Impulse Technology creates cutting-edge prosthetic and rehabilitation systems with below-the-knee components that replicate natural leg movements. Their innovative products enhance mechanical and energy applications, revolutionizing the field of prosthetics.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

National Rank (United States)

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Regional Rank (North America)

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SB Score:179

CTFGuide is a platform for cybersecurity talent, using AI and virtual scenarios to assess skills in cybersecurity, cloud native, and more. Join us at the intersection of technology and talent development.

Industry:
Software & Data
Subindustry:
Cybersecurity

National Rank (United States)

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Regional Rank (North America)

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SB Score:176

Rewire Health's learning platform offers personalized culinary medicine to enhance engagement, health, and equity within organizations. By utilizing white-label solutions and seamless integrations, health organizations can elevate member engagement, gain valuable insights, and reduce overhead costs.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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Regional Rank (North America)

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Total amount:20

Top 7 Software & Data Startups in State College for 2025

The top three Software & Data startups in State College have raised more than USD 37.5M. State College startup ecosystem ranks #474 globally for the Software & Data industry.
SB Score:351

We sell Mobile Apps for schools, enterprises and design/photography. Our products include: The Kdan Cloud, Software Development Kits, Animation Desk, Pocket Snapper, Pdf Connoisseur, Note ledge and many more.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:310

Analytical Flavor Systems’ AI-driven Gastrograph platform helps packaged food companies achieve greater success in a saturated food industry that has an over 80% failure rate. Gastograph moves CPG brands’ development process beyond traditional tasting panels, it surveys each product with a flavor profile engine that is predictive, anticipating how new foods will perform in different markets, over a long time horizon, and against various demographic archetypes. Food companies are struggling to launch new products in an era of rapidly shifting consumer tastes, and an AI-driven platform like Gastrograph gives big food a more accurate map with which to navigate into the future.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:179

CTFGuide is a platform for cybersecurity talent, using AI and virtual scenarios to assess skills in cybersecurity, cloud native, and more. Join us at the intersection of technology and talent development.

Industry:
Software & Data
Subindustry:
Cybersecurity

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:7

Top 6 Hardware & IoT Startups in State College for 2025

The top three Hardware & IoT startups in State College have raised more than USD 28.5M. State College startup ecosystem ranks among the top 10 locations in the world for startups in Hardware & IoT, holding the falseth position.
SB Score:295

spotLESS Materials is driven by a dedicated research team of experts in materials, mechanical, and bio-inspired engineering. They actively tackle global challenges and commercial opportunities through innovative research projects, creating advanced solutions that address pressing needs in various industries.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:169

Spectacles Studio, a subsidiary of Lens, specializes in capturing immersive content designed for integration with Snapchat. By creating innovative lenses, it empowers users to enhance their storytelling and engage audiences in dynamic new ways, enriching the Snapchat experience with unique visual elements.

Industry:
Hardware & IoT
Subindustry:
3D Printing

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:6

Top 2 Healthtech Startups in State College for 2025

The top three Healthtech startups in State College have raised more than USD 27.5M. State College startup ecosystem ranks among the top 10 locations in the world for startups in Healthtech, holding the falseth position.
SB Score:313

NeuExcell is an early stage gene therapy company focusing on neurodegenerative diseases. We have developed a disruptive neural repair technology that utilizes in vivo astrocyte-to-neuron conversion. Our vision is to improve the quality of life of millions of patients worldwide who are suffering from neurodegenerative conditions by using the power of gene therapy to restore damaged neural tissue.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:221

Aleo BME, Inc. is a biotechnology R&D company based in State College, Pennsylvania, dedicated to advancing innovative solutions in healthcare. By leveraging cutting-edge research and technology, Aleo BME aims to transform scientific discoveries into impactful therapies that improve patient outcomes and enhance quality of life.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:2

Most Funded Startups in State College for 2025

The top three most funded startups in State College have raised total funding of more than USD 85.1M. Phospholutions has 0.50% more funding than NeuExcell Therapeutics.
SB Score:320

Phospholutions, a State College, PA startup, offers sustainable fertilizers. Their innovative products help improve crop growth while minimizing environmental impact.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:313

NeuExcell is an early stage gene therapy company focusing on neurodegenerative diseases. We have developed a disruptive neural repair technology that utilizes in vivo astrocyte-to-neuron conversion. Our vision is to improve the quality of life of millions of patients worldwide who are suffering from neurodegenerative conditions by using the power of gene therapy to restore damaged neural tissue.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:20

Top Hiring Startups in State College by Employee Number

The top three hiring startups in State College have an median employee size that is between [51-100]
SB Score:284

Videon develops products for audio/video applications in the Global AV, Aviation, and Automotive industries. With over 30 million devices using its streaming media, DVD, and Blu-ray technology, Videon is a partner to the world technology companies and AV product developers. Its holistic approach supports customers at any stage in product development, offering expertise during ideation, design, development, manufacturing, certification, and support. All of these are done in-house, simplifying, and streamlining the process. Since its founding, Videon has achieved a number of industry firsts, including the first universal Blu-ray Disc and HD DVD player and the first optical disc Google TV. Our Android app Avia was one of the first apps to be released with support for Google Chromecast, and for weeks Avia was the most popular Android app. It’s been downloaded over a million times. Videon continues to grow and expand into new industries, and we have made the Inc. 5000 list of America’s fastest-growing private companies four times.

Industry:
Social & Leisure
Subindustry:
Entertainment

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:320

Phospholutions, a State College, PA startup, offers sustainable fertilizers. Their innovative products help improve crop growth while minimizing environmental impact.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:313

NeuExcell is an early stage gene therapy company focusing on neurodegenerative diseases. We have developed a disruptive neural repair technology that utilizes in vivo astrocyte-to-neuron conversion. Our vision is to improve the quality of life of millions of patients worldwide who are suffering from neurodegenerative conditions by using the power of gene therapy to restore damaged neural tissue.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:310

Analytical Flavor Systems’ AI-driven Gastrograph platform helps packaged food companies achieve greater success in a saturated food industry that has an over 80% failure rate. Gastograph moves CPG brands’ development process beyond traditional tasting panels, it surveys each product with a flavor profile engine that is predictive, anticipating how new foods will perform in different markets, over a long time horizon, and against various demographic archetypes. Food companies are struggling to launch new products in an era of rapidly shifting consumer tastes, and an AI-driven platform like Gastrograph gives big food a more accurate map with which to navigate into the future.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:20

Explore the Startup Ecosystem of State College

National Rank

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Regional Rank

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178th

4

Global Rank

(WorldWide)

552nd

11

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Top Cities for Startups in United States - Ranked by StartupBlink

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Quantity Score
Quality ScoreBusiness Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
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