282 Top startups in St. Louis for January 2025

We rank Lumeris, Adalo and Clever Real Estate in St. Louis along with 279 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. St. Louis ranks #115 globally and #40 in United States.

Powered by:

Category

Startups

Unicorns

Exits

Coworking Spaces

Accelerators

Best Startups in St. Louis for 2025

SB Score:523

Lumeris is an innovative company transforming accountable care delivery. They provide cutting-edge solutions to improve healthcare outcomes and lower costs.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:522

Adalo is a tech company focused on Android, software, and IT. Specializing in creating innovative solutions, they offer cutting-edge products for businesses and individuals. With a passion for technology, Adalo strives to make complex systems accessible and user-friendly for all.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:492

Specializing in commercial real estate and online marketplace, this innovative Real Estate company offers a seamless platform for buyers and sellers. With a focus on efficiency and expertise, they provide a one-stop solution for all your commercial property needs.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:466

Playbite is a vibrant social gaming platform that enables users to connect, play, earn rewards, and compete in exciting games. Founded by Diego Kafie, Stu Feldt, and Nic Weber, Playbite fosters a dynamic community where gaming meets social interaction.

Industry:
Edtech
Subindustry:
Edtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:464

Surround Care is dedicated to enhancing healthcare by improving affordability, quality, access, and the overall patient experience for everyone. Their innovative solutions aim to make healthcare more accessible and effective, ensuring that all individuals receive the care they deserve.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:436

Travel in style and comfort with wardrobe essentials that are perfect for both the journey and the destination. Our collection of clothing and accessories ensures you look and feel your best no matter where you go.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:435

Balto enhances contact center performance by providing real-time guidance to boost conversions, improve customer experience, and reduce ramp time.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:430

Capacity is an AI-powered helpdesk that streamlines customer and employee support through automation. Enhance efficiency and satisfaction with this innovative solution.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:429

Geneoscopy is revolutionizing colorectal cancer screening with a noninvasive stool sample test. Our innovative biomarker technology detects cancer early, making diagnosis easier and more accessible. Join us in the fight against colorectal cancer.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:424

Native Pet offers organic, highly effective supplements for dogs and cats. With limited ingredients, their products provide optimal nutrition for pets.

Industry:
Foodtech
Subindustry:
Food and Beverage

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:422

Revolutionize HR with a cutting-edge SaaS platform for performance management, learning, and rewards. Drive engagement and boost productivity with our innovative technology, designed to optimize employee performance.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:282

Top 53 Healthtech Startups in St. Louis for 2025

The top three Healthtech startups in St. Louis have raised more than USD 1.02B. St. Louis ranks #50 globally for the Healthtech industry.
SB Score:523

Lumeris is an innovative company transforming accountable care delivery. They provide cutting-edge solutions to improve healthcare outcomes and lower costs.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:464

Surround Care is dedicated to enhancing healthcare by improving affordability, quality, access, and the overall patient experience for everyone. Their innovative solutions aim to make healthcare more accessible and effective, ensuring that all individuals receive the care they deserve.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:429

Geneoscopy is revolutionizing colorectal cancer screening with a noninvasive stool sample test. Our innovative biomarker technology detects cancer early, making diagnosis easier and more accessible. Join us in the fight against colorectal cancer.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:53

Top 73 Software & Data Startups in St. Louis for 2025

The top three Software & Data startups in St. Louis have raised more than USD 192M. St. Louis ranks #133 globally for the Software & Data industry.
SB Score:522

Adalo is a tech company focused on Android, software, and IT. Specializing in creating innovative solutions, they offer cutting-edge products for businesses and individuals. With a passion for technology, Adalo strives to make complex systems accessible and user-friendly for all.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:435

Balto enhances contact center performance by providing real-time guidance to boost conversions, improve customer experience, and reduce ramp time.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:430

Capacity is an AI-powered helpdesk that streamlines customer and employee support through automation. Enhance efficiency and satisfaction with this innovative solution.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:73

Top 33 Ecommerce & Retail Startups in St. Louis for 2025

The top three Ecommerce & Retail startups in St. Louis have raised more than USD 43.8M. St. Louis ranks #140 globally for the Ecommerce & Retail industry.
SB Score:492

Specializing in commercial real estate and online marketplace, this innovative Real Estate company offers a seamless platform for buyers and sellers. With a focus on efficiency and expertise, they provide a one-stop solution for all your commercial property needs.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:436

Travel in style and comfort with wardrobe essentials that are perfect for both the journey and the destination. Our collection of clothing and accessories ensures you look and feel your best no matter where you go.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:420

Customily empowers customers to easily personalize products online. With our user-friendly e-commerce platform, users can create unique items by adding their personal touch. Say goodbye to cookie-cutter products and hello to customized goods tailored just for you.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:33

Most Funded Startups in St. Louis for 2025

The top three most funded startups in St. Louis have raised total funding of more than USD 1.02B. Surround Care has 1.08% more funding than Lumeris.
SB Score:464

Surround Care is dedicated to enhancing healthcare by improving affordability, quality, access, and the overall patient experience for everyone. Their innovative solutions aim to make healthcare more accessible and effective, ensuring that all individuals receive the care they deserve.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:523

Lumeris is an innovative company transforming accountable care delivery. They provide cutting-edge solutions to improve healthcare outcomes and lower costs.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:408

Wugen is creating ready-to-use cellular therapies for treating solid tumors and blood cancers.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:282

Top Hiring Startups in St. Louis by Employee Number

The top three hiring startups in St. Louis have an median employee size that is between [1001-5000]
SB Score:523

Lumeris is an innovative company transforming accountable care delivery. They provide cutting-edge solutions to improve healthcare outcomes and lower costs.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:464

Surround Care is dedicated to enhancing healthcare by improving affordability, quality, access, and the overall patient experience for everyone. Their innovative solutions aim to make healthcare more accessible and effective, ensuring that all individuals receive the care they deserve.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:376

EmpowerMe enhances senior living communities by offering top-notch, integrated on-site therapy, diagnostics, and primary care services. By providing comprehensive health solutions, it ensures residents receive the support they need, fostering a healthier and more vibrant living environment.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:282

Explore the Startup Ecosystem of St. Louis

National Rank

(undefined)

40th

3

Regional Rank

(undefined)

46th

3

Global Rank

(WorldWide)

115th

3

Visit
Top Cities for Startups in United States - Ranked by StartupBlink
StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
Pro
2024 National Rank CityGlobal RankTotal Score

Access subscores for 1000 cities and 100 countries

Quantity Score
Quality ScoreBusiness Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
Microsoft Excel icon
Download CSV file
Pro