81 Top startups in South San Francisco for January 2025

We rank Plenty, Birst and Freenome in South San Francisco along with 78 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. South San Francisco is part of San Francisco Bay which ranks #1 globally and #1 in North America.

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Best Startups in South San Francisco for 2025

SB Score:566

Plenty is a vertical farming company delivering fresh, pesticide-free produce to customers. Get your hands on high-quality greens without harmful chemicals.

Industry:
Foodtech
Subindustry:
Agtech

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SB Score:549

Birst empowers users to easily create and use analytical applications without needing specialized skills. By automating complex tasks, this platform simplifies the process for regular individuals, making business intelligence more accessible and efficient.

Industry:
Software & Data
Subindustry:
SaaS

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SB Score:537

Freenome designs personalized health plans for individuals, promoting wellness through tailored solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:491

ArsenalBio develops customizable cell therapies for various medical applications. Their innovative approach allows for precise programming of cells to target specific diseases, offering promising new treatment options.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:490

Insitro uses machine learning and biology to revolutionize drug discovery. Their innovative approach transforms the process, making it more efficient and effective.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:478

Bright Pattern offers cutting-edge multichannel cloud contact center software, empowering businesses to efficiently engage with customers.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:476

Glydways creates autonomous transportation solutions using clean energy technology. Their vehicles are designed to provide efficient and sustainable transportation options for users.

Industry:
Transportation
Subindustry:
Transportation-Other

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SB Score:474

Cellares revolutionizes cell therapy manufacturing, streamlining processes for optimal efficiency. Their innovative technology enhances production capabilities, leading the way in the advancement of regenerative medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:457

Carrum Health is a platform connecting individuals with scheduled medical procedures. Access top-tier healthcare providers at competitive prices. Experience hassle-free coordination and payment for your treatment.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:447

Emerald Cloud Lab creates cutting-edge technology for biotech innovation. Their platforms drive the future of research, making it easier and more efficient for scientists to conduct experiments and develop new solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:81

Top 11 Software & Data Startups in South San Francisco for 2025

The top three Software & Data startups in South San Francisco have raised more than USD 1.02B. South San Francisco is part of San Francisco Bay which ranks #1 globally for the Software & Data industry.
SB Score:549

Birst empowers users to easily create and use analytical applications without needing specialized skills. By automating complex tasks, this platform simplifies the process for regular individuals, making business intelligence more accessible and efficient.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

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Regional Rank (North America)

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SB Score:491

ArsenalBio develops customizable cell therapies for various medical applications. Their innovative approach allows for precise programming of cells to target specific diseases, offering promising new treatment options.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Regional Rank (North America)

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SB Score:478

Bright Pattern offers cutting-edge multichannel cloud contact center software, empowering businesses to efficiently engage with customers.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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Regional Rank (North America)

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Total amount:11

Top 2 Fintech Startups in South San Francisco for 2025

The top three Fintech startups in South San Francisco have raised more than USD 13.9M. South San Francisco is part of San Francisco Bay which ranks #1 globally for the Fintech industry.
SB Score:328

Dama Financial offers financial services for businesses in restricted industries. Simplifying banking solutions, Dama provides safe and compliant transactions for industries such as cannabis and hemp.

Industry:
Fintech
Subindustry:
Online Banking

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SB Score:222

Coinroll is a Delaware C corporation creating coinroll.app, a fintech platform for institutional investors. The platform streamlines digital investments, offering real-time insights on new opportunities.

Industry:
Fintech
Subindustry:
Cryptocurrency

National Rank (United States)

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Regional Rank (North America)

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Total amount:2

Top 50 Healthtech Startups in South San Francisco for 2025

The top three Healthtech startups in South San Francisco have raised more than USD 2.36B. South San Francisco is part of San Francisco Bay which ranks #1 globally for the Healthtech industry.
SB Score:537

Freenome designs personalized health plans for individuals, promoting wellness through tailored solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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SB Score:490

Insitro uses machine learning and biology to revolutionize drug discovery. Their innovative approach transforms the process, making it more efficient and effective.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:474

Cellares revolutionizes cell therapy manufacturing, streamlining processes for optimal efficiency. Their innovative technology enhances production capabilities, leading the way in the advancement of regenerative medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:50

Most Funded Startups in South San Francisco for 2025

The top three most funded startups in South San Francisco have raised total funding of more than USD 2.96B. Freenome has 0.41% more funding than Plenty.
SB Score:537

Freenome designs personalized health plans for individuals, promoting wellness through tailored solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:566

Plenty is a vertical farming company delivering fresh, pesticide-free produce to customers. Get your hands on high-quality greens without harmful chemicals.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:490

Insitro uses machine learning and biology to revolutionize drug discovery. Their innovative approach transforms the process, making it more efficient and effective.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:81

Top Hiring Startups in South San Francisco by Employee Number

The top three hiring startups in South San Francisco have an median employee size that is between [251-500]
SB Score:537

Freenome designs personalized health plans for individuals, promoting wellness through tailored solutions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:566

Plenty is a vertical farming company delivering fresh, pesticide-free produce to customers. Get your hands on high-quality greens without harmful chemicals.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:549

Birst empowers users to easily create and use analytical applications without needing specialized skills. By automating complex tasks, this platform simplifies the process for regular individuals, making business intelligence more accessible and efficient.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:491

ArsenalBio develops customizable cell therapies for various medical applications. Their innovative approach allows for precise programming of cells to target specific diseases, offering promising new treatment options.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:81

Explore the Startup Ecosystem of South San Francisco

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Top Cities for Startups in United States - Ranked by StartupBlink
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Quantity Score
Quality ScoreBusiness Score
1st
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1st
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710.966
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2nd
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2nd
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251.377
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00.00
3rd
0
4th
0
121.937
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00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
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