74 Top startups in Rockville for April 2025

We rank DrFirst, XENERGY and Rate My Band in Rockville along with 71 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Rockville is part of Washington DC Area startup ecosystem which ranks #19 globally and #8 in North America.

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Best Startups in Rockville for 2025

SB Score:577

DrFirst offers healthcare providers secure messaging, e-prescribing, and EHR software solutions. Simplifying communication and record-keeping, their tools enhance efficiency and compliance.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:548

X-energy designs advanced nuclear reactors and fuel. Their innovative engineering solutions provide clean and reliable energy.

Industry:
Energy & Environment
Subindustry:
Clean Energy

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SB Score:527

Ratemyband.com is a vibrant community where musicians, fans, and venues can connect. Musicians can easily promote their music, fans can discover new bands effortlessly, and venues can showcase themselves to a wide audience. It's the ultimate destination for all music lovers to come together and share their passion.

Industry:
Social & Leisure
Subindustry:
Entertainment

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SB Score:486

AutoSled is revolutionizing automotive logistics with a cutting-edge platform and marketplace. Streamlining the transportation process, they offer a seamless solution for industry professionals.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:429

Curbio partners with real estate agents and homeowners to deliver a smart and hassle-free home improvement experience designed to get every home on the market and sold fast.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:427

CloudBolt streamlines hybrid cloud management and enhances automation strategies for enterprises. Simplify your cloud operations with our innovative software.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:425

Sepio has created the first asset risk management platform that operates on asset existence rather than activity. Using physical layer asset DNA profiling, our solution provides customers with actionable visibility, policy enforcement and mitigation capabilities. These allow our customers to gain better control of all assets at scale. With trafficless monitoring, our solution is asset agnostic - whether your infrastructure is connected to IT/OT/IOT. Within 24 hours, Sepio's solution will report what assets you actually have with their respective asset risk factor and help you achieve a stronger cybersecurity posture.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:397

Founded in 2000, 20/20 GeneSystems offers a cutting-edge proteomics product line for drug development. Their innovative solutions help researchers analyze proteins more effectively, paving the way for advancements in personalized medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:391

3CLogic offers a cloud contact center platform for service desks and sales teams, enabling seamless multichannel communications. Streamline your customer interactions with this innovative solution.

Industry:
Software & Data
Subindustry:
Comtech

National Rank (United States)

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Regional Rank (North America)

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Total amount:74

Top 18 Software & Data Startups in Rockville for 2025

The top three Software & Data startups in Rockville have raised more than USD 183M. Rockville is part of Washington DC Area startup ecosystem which ranks #11 globally for the Software & Data industry.
SB Score:486

AutoSled is revolutionizing automotive logistics with a cutting-edge platform and marketplace. Streamlining the transportation process, they offer a seamless solution for industry professionals.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:427

CloudBolt streamlines hybrid cloud management and enhances automation strategies for enterprises. Simplify your cloud operations with our innovative software.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:425

Sepio has created the first asset risk management platform that operates on asset existence rather than activity. Using physical layer asset DNA profiling, our solution provides customers with actionable visibility, policy enforcement and mitigation capabilities. These allow our customers to gain better control of all assets at scale. With trafficless monitoring, our solution is asset agnostic - whether your infrastructure is connected to IT/OT/IOT. Within 24 hours, Sepio's solution will report what assets you actually have with their respective asset risk factor and help you achieve a stronger cybersecurity posture.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Total amount:18

Top 24 Healthtech Startups in Rockville for 2025

The top three Healthtech startups in Rockville have raised more than USD 258M. Rockville is part of Washington DC Area startup ecosystem which ranks #10 globally for the Healthtech industry.
SB Score:577

DrFirst offers healthcare providers secure messaging, e-prescribing, and EHR software solutions. Simplifying communication and record-keeping, their tools enhance efficiency and compliance.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:397

Founded in 2000, 20/20 GeneSystems offers a cutting-edge proteomics product line for drug development. Their innovative solutions help researchers analyze proteins more effectively, paving the way for advancements in personalized medicine.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:24

Top 2 Fintech Startups in Rockville for 2025

The top three Fintech startups in Rockville have raised more than USD 232M. Rockville is part of Washington DC Area startup ecosystem which ranks #31 globally for the Fintech industry.
SB Score:429

Curbio partners with real estate agents and homeowners to deliver a smart and hassle-free home improvement experience designed to get every home on the market and sold fast.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (United States)

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Regional Rank (North America)

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SB Score:186

Chorus One constructs staking infrastructure for Proof-of-Stake networks, simplifying validation processes.

Industry:
Fintech
Subindustry:
Fintech-Other

National Rank (United States)

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Regional Rank (North America)

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Total amount:2

Most Funded Startups in Rockville for 2025

The top three most funded startups in Rockville have raised total funding of more than USD 1.93B. XENERGY has 5.63% more funding than Curbio.
SB Score:548

X-energy designs advanced nuclear reactors and fuel. Their innovative engineering solutions provide clean and reliable energy.

Industry:
Energy & Environment
Subindustry:
Clean Energy

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:429

Curbio partners with real estate agents and homeowners to deliver a smart and hassle-free home improvement experience designed to get every home on the market and sold fast.

Industry:
Fintech
Subindustry:
Financial Services

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:577

DrFirst offers healthcare providers secure messaging, e-prescribing, and EHR software solutions. Simplifying communication and record-keeping, their tools enhance efficiency and compliance.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:74

Top Hiring Startups in Rockville by Employee Number

The top three hiring startups in Rockville have an median employee size that is between [501-1000]
SB Score:276

US Fertility is a premier fertility practice, led by physicians dedicated to enhancing patient care. With a focus on innovation and best practices, it aims to improve treatment outcomes and elevate the overall patient experience in the journey to parenthood.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:577

DrFirst offers healthcare providers secure messaging, e-prescribing, and EHR software solutions. Simplifying communication and record-keeping, their tools enhance efficiency and compliance.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:548

X-energy designs advanced nuclear reactors and fuel. Their innovative engineering solutions provide clean and reliable energy.

Industry:
Energy & Environment
Subindustry:
Clean Energy

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:74

Explore the Startup Ecosystem of Rockville

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Regional Rank

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8th

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Global Rank

(WorldWide)

19th

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
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1
37.971
00.00
00.00
00.00
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0
24th
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2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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