17 Top startups in Novi for April 2025

We rank Delphinus Medical Technologies, Centria Healthcare and Noble Gas Systems in Novi along with 14 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Novi is part of Detroit startup ecosystem which ranks #62 globally and #26 in North America.

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Accelerators

Top Unicorn Startups in Novi for 2025

Our Next Energy is the only unicorn in Novi raising more than USD 1.2B. It is the undefined ranked unicorn in North America.
SB Score:472

Our Next Energy is a developer of energy storage technology to expand access to sustainable power. Our Next Energy focuses on safer battery chemistries that use sustainable raw materials while creating a reliable, low cost and conflict-free supply chain. The company was founded in 2020 and is based in Novi, Michigan.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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Total amount:1

Best Startups in Novi for 2025

Delphinus Medical Technologies offers advanced breast cancer screening solutions for hospitals and imaging clinics. Their technology helps healthcare providers detect breast cancer more effectively, ultimately improving patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:330

Centria Healthcare offers innovative healthcare solutions. Specializing in providing high-quality care, they strive to improve the well-being of individuals through customized services. With a focus on excellence, they are dedicated to enhancing the overall healthcare experience for all.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:292

Noble Gas Systems, founded in 2017 and based in Novi, Michigan, specializes in developing innovative gas storage and delivery systems. Their cutting-edge technology includes conformable tank design, providing efficient solutions for various industries.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:282

Upkara specializes in developing biopreservation technologies, revolutionizing the field of biotechnology. Their innovative solutions ensure the safe storage and longevity of biological materials.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:241

MDI Therapeutics is a cutting-edge company dedicated to developing innovative treatments for fibrotic diseases. Specializing in discovery stage research, they aim to revolutionize the field and improve the lives of those affected by these conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:168

Le Car is a user-friendly car shopping tool created by journalists, offering personalized recommendations to simplify decision-making.

Industry:
Marketing & Sales
Subindustry:
Market Research

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SB Score:124

Delivers unique travel experiences through personalized itineraries and curated activities.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:105

KochaSoft creates a cutting-edge learning and content management system for enterprises to efficiently train employees and stakeholders in vital skills and programs for the future.

Industry:
Software & Data
Subindustry:
Cloud

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Streamline IT Services is a specialized provider of IT and marketing solutions, offering services such as CRM, ERP, email list and database building, and campaign management. They enhance data quality through data licensing, hygiene, enrichment, and email marketing, empowering businesses to optimize their outreach and engagement strategies.

Industry:
Marketing & Sales
Subindustry:
CRM

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SB Score:86

EmployEz offers a cloud-based HR management solution for small and mid-size companies, providing comprehensive workforce management capabilities. Committed to helping clients succeed with tailored solutions, EmployEz Services ensures efficient and effective human resource management for businesses of all sizes.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:74

Easily integrate Xero, QuickBooks, HubSpot, and AWS with Google Sheets and G Suite using powerful add-ons. Streamline your cloud applications for seamless financial management, marketing automation, and cloud computing.

Industry:
Software & Data
Subindustry:
Cloud

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Total amount:17

Top 7 Software & Data Startups in Novi for 2025

The top three Software & Data startups in Novi have raised more than USD 20K. Novi is part of Detroit startup ecosystem which ranks #67 globally for the Software & Data industry.
SB Score:124

Delivers unique travel experiences through personalized itineraries and curated activities.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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SB Score:105

KochaSoft creates a cutting-edge learning and content management system for enterprises to efficiently train employees and stakeholders in vital skills and programs for the future.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

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Regional Rank (North America)

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SB Score:86

EmployEz offers a cloud-based HR management solution for small and mid-size companies, providing comprehensive workforce management capabilities. Committed to helping clients succeed with tailored solutions, EmployEz Services ensures efficient and effective human resource management for businesses of all sizes.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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Total amount:7

Top 1 Ecommerce & Retail Startups in Novi for 2025

Novi is part of Detroit startup ecosystem which ranks #47 globally for the Ecommerce & Retail industry.
SB Score:23

Panda CashBack rewards online shoppers with cashback rebates and coupons from over 2500+ online stores and local deals in the U.S. and Canada. Shop through affiliate partners to earn rewards for your purchases.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Total amount:1

Top 4 Healthtech Startups in Novi for 2025

The top three Healthtech startups in Novi have raised more than USD 134M. Novi is part of Detroit startup ecosystem which ranks #53 globally for the Healthtech industry.

Delphinus Medical Technologies offers advanced breast cancer screening solutions for hospitals and imaging clinics. Their technology helps healthcare providers detect breast cancer more effectively, ultimately improving patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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SB Score:330

Centria Healthcare offers innovative healthcare solutions. Specializing in providing high-quality care, they strive to improve the well-being of individuals through customized services. With a focus on excellence, they are dedicated to enhancing the overall healthcare experience for all.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

0

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SB Score:282

Upkara specializes in developing biopreservation technologies, revolutionizing the field of biotechnology. Their innovative solutions ensure the safe storage and longevity of biological materials.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:4

Most Funded Startups in Novi for 2025

The top three most funded startups in Novi have raised total funding of more than USD 141M. Delphinus Medical Technologies has 5.76% more funding than Upkara.

Delphinus Medical Technologies offers advanced breast cancer screening solutions for hospitals and imaging clinics. Their technology helps healthcare providers detect breast cancer more effectively, ultimately improving patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:282

Upkara specializes in developing biopreservation technologies, revolutionizing the field of biotechnology. Their innovative solutions ensure the safe storage and longevity of biological materials.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:292

Noble Gas Systems, founded in 2017 and based in Novi, Michigan, specializes in developing innovative gas storage and delivery systems. Their cutting-edge technology includes conformable tank design, providing efficient solutions for various industries.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:17

Top Hiring Startups in Novi by Employee Number

The top three hiring startups in Novi have an median employee size that is between [101-250]
SB Score:330

Centria Healthcare offers innovative healthcare solutions. Specializing in providing high-quality care, they strive to improve the well-being of individuals through customized services. With a focus on excellence, they are dedicated to enhancing the overall healthcare experience for all.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:105

KochaSoft creates a cutting-edge learning and content management system for enterprises to efficiently train employees and stakeholders in vital skills and programs for the future.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Delphinus Medical Technologies offers advanced breast cancer screening solutions for hospitals and imaging clinics. Their technology helps healthcare providers detect breast cancer more effectively, ultimately improving patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:292

Noble Gas Systems, founded in 2017 and based in Novi, Michigan, specializes in developing innovative gas storage and delivery systems. Their cutting-edge technology includes conformable tank design, providing efficient solutions for various industries.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:17

Explore the Startup Ecosystem of Novi

National Rank

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Regional Rank

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26th

1

Global Rank

(WorldWide)

62nd

6

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
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4
41.259
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00.00
00.00
8th
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1
19th
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1
37.971
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00.00
00.00
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0
24th
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2
34.098
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00.00
00.00
10th
0
25th
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1
33.768
00.00
00.00
00.00
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