21 Top startups in Natick for January 2025

We rank Ventus Therapeutics, Sionna Therapeutics and Garuda Therapeutics in Natick along with 18 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Natick is part of Boston Area which ranks #5 globally and #4 in North America.

Powered by:

Category

Startups

Unicorns

Exits

Coworking Spaces

Accelerators

Best Startups in Natick for 2025

SB Score:416

Sionna Therapeutics, established in late 2019, harnesses a decade of scientific investment from large pharmaceutical companies. With a dedicated team of experts, the company is committed to restoring normal CFTR function, aiming to transform the lives of those affected by cystic fibrosis.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:403

Garuda Therapeutics creates ready-to-use stem cell treatments for severe diseases, providing hope for those facing life-threatening conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:397

Introducing Planning Maestro: revolutionizing financial planning with intelligent analytics for modern finance offices. Streamline operations, improve decision-making, and boost productivity with this innovative platform.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:388

Empassion Health offers comprehensive care services for patients with advanced illnesses. Founded in 2022, the company focuses on providing quality support and treatment for those in need.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:376

Allorion Therapeutics develops small molecule therapies for cancer and autoimmune diseases. Their focus is on creating innovative treatments to improve patient outcomes.

Industry:
Healthtech
Subindustry:
Medtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

11th

DOTS
SB Score:326

DOTS is revolutionizing point of care detection with a groundbreaking diagnostics platform for consumers and industries. This innovative technology is changing the game in rapid detection, making it easier and more accessible than ever before.

Industry:
Healthtech
Subindustry:
Health-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:21

Top 14 Healthtech Startups in Natick for 2025

The top three Healthtech startups in Natick have raised more than USD 796M. Natick is part of Boston Area which ranks #2 globally for the Healthtech industry.
SB Score:416

Sionna Therapeutics, established in late 2019, harnesses a decade of scientific investment from large pharmaceutical companies. With a dedicated team of experts, the company is committed to restoring normal CFTR function, aiming to transform the lives of those affected by cystic fibrosis.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:403

Garuda Therapeutics creates ready-to-use stem cell treatments for severe diseases, providing hope for those facing life-threatening conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:14

Top 3 Software & Data Startups in Natick for 2025

The top three Software & Data startups in Natick have raised more than USD 32.6M. Natick is part of Boston Area which ranks #5 globally for the Software & Data industry.
SB Score:397

Introducing Planning Maestro: revolutionizing financial planning with intelligent analytics for modern finance offices. Streamline operations, improve decision-making, and boost productivity with this innovative platform.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:306

Salesroom aims to be the leading remote selling platform for mid-market and enterprise B2B account executives, empowering them to enhance their sales processes and engage clients effectively. With innovative tools and features, it streamlines remote interactions, helping teams close deals faster and build lasting relationships.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:168

BrowserUp offers cutting-edge automation tools to streamline testing processes, enabling teams to catch bugs sooner in the development cycle. Boost your release cycle efficiency with BrowserUp's innovative solutions.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:3

Most Funded Startups in Natick for 2025

The top three most funded startups in Natick have raised total funding of more than USD 796M. Ventus Therapeutics has 0.27% more funding than Sionna Therapeutics.
SB Score:416

Sionna Therapeutics, established in late 2019, harnesses a decade of scientific investment from large pharmaceutical companies. With a dedicated team of experts, the company is committed to restoring normal CFTR function, aiming to transform the lives of those affected by cystic fibrosis.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:403

Garuda Therapeutics creates ready-to-use stem cell treatments for severe diseases, providing hope for those facing life-threatening conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:21

Top Hiring Startups in Natick by Employee Number

The top three hiring startups in Natick have an median employee size that is between [51-100]
SB Score:397

Introducing Planning Maestro: revolutionizing financial planning with intelligent analytics for modern finance offices. Streamline operations, improve decision-making, and boost productivity with this innovative platform.

Industry:
Software & Data
Subindustry:
Data Analytics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:303

At Wasabi, enjoy simple, flavorful, and healthy food. Indulge in dishes that embody these qualities, delivered straight to your table.

Industry:
Foodtech
Subindustry:
Food Manufacturing

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:21

Explore the Startup Ecosystem of Natick

National Rank

(undefined)

4th

0

Regional Rank

(undefined)

4th

0

Global Rank

(WorldWide)

5th

0

Visit
Top Cities for Startups in United States - Ranked by StartupBlink
StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
Pro
2024 National Rank CityGlobal RankTotal Score

Access subscores for 1000 cities and 100 countries

Quantity Score
Quality ScoreBusiness Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
Microsoft Excel icon
Download CSV file
Pro