23 Top startups in Lowell for January 2025

We rank American Mojo, Dassault Systèmes Enovia and ePropelled in Lowell along with 20 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Lowell is part of Boston Area which ranks #5 globally and #4 in North America.

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Best Startups in Lowell for 2025

SB Score:506

American MoJo aimed to show social impact through a for-profit model by creating living wage apparel jobs in the US, offering free childcare to empower low-income single mothers to build sustainable careers. Providing education, financial management, and career counseling, the goal was to create long-term success for families.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

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Dassault Systèmes Enovia offers cutting-edge collaborative product lifecycle management solutions for businesses. Users can streamline processes, enhance communication, and increase efficiency with this innovative technology.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:384

ePropelled specializes in creating smart motors, controllers, generators, and power systems. Their cutting-edge technology revolutionizes how energy is managed and utilized, making them a leader in the industry.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:369

RevBio is creating a groundbreaking bone adhesive for repairing fractures and securing metal implants.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:345

This startup improves prostate disease management with innovative solutions. It offers a range of tools and resources to help individuals track symptoms, monitor progress, and access personalized treatment plans.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:319

Z-Polymers is a clean-tech materials science company dedicated to addressing essential challenges in critical industries. By developing innovative solutions, it enhances sustainability and performance, making a significant impact on sectors that rely on advanced materials for their operations.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:289

ArthroMeda is an innovative navigation system using sensors for hip replacement surgery. It offers precise guidance and is protected by patents.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:277

Phase Two Chemicals is an innovative clean chemistry company pioneering on-site hydrogen peroxide production technology, enabling businesses to generate this essential compound efficiently and sustainably. Their breakthrough approach not only enhances operational safety but also reduces environmental impact, making it a game-changer in the chemical industry.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:261

Advanced Silicon Group provides cutting-edge silicon nanotechnology services. They specialize in offering innovative solutions for companies looking to enhance their products with the latest advancements in silicon technology.

Industry:
Energy & Environment
Subindustry:
Energy

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Total amount:23

Top 8 Healthtech Startups in Lowell for 2025

The top three Healthtech startups in Lowell have raised more than USD 84.6M. Lowell is part of Boston Area which ranks #2 globally for the Healthtech industry.
SB Score:369

RevBio is creating a groundbreaking bone adhesive for repairing fractures and securing metal implants.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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SB Score:345

This startup improves prostate disease management with innovative solutions. It offers a range of tools and resources to help individuals track symptoms, monitor progress, and access personalized treatment plans.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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Total amount:8

Top 5 Software & Data Startups in Lowell for 2025

The top three Software & Data startups in Lowell have raised more than USD 975K. Lowell is part of Boston Area which ranks #5 globally for the Software & Data industry.

Dassault Systèmes Enovia offers cutting-edge collaborative product lifecycle management solutions for businesses. Users can streamline processes, enhance communication, and increase efficiency with this innovative technology.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:215

Weave offers the only open-source software for analyzing and visualizing vast datasets from multiple platforms. It empowers users to seamlessly integrate, process, and interpret complex information, driving informed decisions and innovative insights.

Industry:
Software & Data
Subindustry:
Data Analytics

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SB Score:181

Leonine Technologies is a research and development firm that specializes in creating innovative business models and providing expert product design services, empowering startups and established companies to transform their ideas into successful market-ready solutions.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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Total amount:5

Top 2 Ecommerce & Retail Startups in Lowell for 2025

The top three Ecommerce & Retail startups in Lowell have raised more than USD 3.88M. Lowell is part of Boston Area which ranks #11 globally for the Ecommerce & Retail industry.
SB Score:506

American MoJo aimed to show social impact through a for-profit model by creating living wage apparel jobs in the US, offering free childcare to empower low-income single mothers to build sustainable careers. Providing education, financial management, and career counseling, the goal was to create long-term success for families.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:24

Linger offers beautifully designed home textiles directly to consumers, partnering with global factories to ensure a transparent and sustainable supply chain. Their focus on inspirational designs and ethical practices makes it easy for customers to enhance their living spaces with quality products that reflect their values.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

National Rank (United States)

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Total amount:2

Most Funded Startups in Lowell for 2025

The top three most funded startups in Lowell have raised total funding of more than USD 84.6M. RevBio has 0.74% more funding than Alcyone Therapeutics.
SB Score:369

RevBio is creating a groundbreaking bone adhesive for repairing fractures and securing metal implants.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:23

Top Hiring Startups in Lowell by Employee Number

The top three hiring startups in Lowell have an median employee size that is between [101-250]

Dassault Systèmes Enovia offers cutting-edge collaborative product lifecycle management solutions for businesses. Users can streamline processes, enhance communication, and increase efficiency with this innovative technology.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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SB Score:125

Titan.ium Platform offers essential network applications that enhance signaling, routing, subscriber data management, and security. By streamlining these core functions, it empowers businesses to optimize their network performance and safeguard user data effectively.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

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Regional Rank (North America)

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SB Score:506

American MoJo aimed to show social impact through a for-profit model by creating living wage apparel jobs in the US, offering free childcare to empower low-income single mothers to build sustainable careers. Providing education, financial management, and career counseling, the goal was to create long-term success for families.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:384

ePropelled specializes in creating smart motors, controllers, generators, and power systems. Their cutting-edge technology revolutionizes how energy is managed and utilized, making them a leader in the industry.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:23

Explore the Startup Ecosystem of Lowell

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Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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109.679
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