137 Top startups in Los Altos for April 2025

We rank Bolster Inc., prezent.ai and Dwellsy in Los Altos along with 134 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Los Altos is part of San Francisco Bay startup ecosystem which ranks #1 globally and #1 in North America.

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Top Unicorn Startups in Los Altos for 2025

Three startups have achieved unicorn status by exceeding USD 1 billion in valuation. Collectively, the top three unicorns in Los Altos have raised more than USD 6.45B.
SB Score:549

Placer.ai provides a traffic analytics platform for generating property insights. Discover valuable data easily and understand foot traffic trends effortlessly.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:340

Cerebras Systems is a cutting-edge hardware startup focused on tackling challenging issues. It is made up of dedicated entrepreneurs working to innovate and solve complex problems.

Industry:
Hardware & IoT
Subindustry:
Hardware

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Total amount:3

Best Startups in Los Altos for 2025

SB Score:470

Bolster uses deep learning to stop counterfeit activity and protect top brands.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:468

Prezent.ai provides an AI-driven platform designed to enhance communication productivity for teams and leaders. By leveraging machine learning, it improves the efficiency and effectiveness of business interactions, empowering users to communicate better and achieve their goals more effectively.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:443

Dwellsy is the top platform for finding rental properties in the U.S, offering the widest selection of listings. Discover your next home with ease on Dwellsy, the go-to marketplace for renters nationwide.

Industry:
Software & Data
Subindustry:
Software

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SB Score:443

Forward Networks, a startup founded and funded by SDN pioneers, aims to revolutionize network control software for more flexible, agile, and automated networks. Join us in driving industry-wide innovation towards a new era of networking.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:441

Spot AI brings Video AI to the physical world, helping organizations see, understand, and improve their workspaces. Built on 1B+ hours of video data and trusted by 1,000+ leading businesses, we deliver measurable ROI in safety, operations, and security across manufacturing floors, retail stores, schools, hospitals, and beyond. Our mission: Turn every camera into a source of business value—helping organizations build safer, smarter, and more efficient spaces.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:435

Descope enables any developer to create secure, frictionless authentication and user journeys for any application. It intends to make customer identity a business enabler.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:431

Alto Neuroscience is a clinical-stage biopharmaceutical company that integrates the biology of the patient into drug development to improve the lives of people with mental health conditions. Through its AI-enabled biomarker platform, Alto Neuroscience combines rich sources of information on patients’ brain activity and behavior to rapidly develop highly-effective medicines for targeted populations. Alto Neuroscience aims to replace today's trial-and-error clinical approach by aligning the right Alto drug with the right patient, redefining psychiatry at a time when the world needs it most.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:428

Rembrand offers online marketing, social media marketing, newsletter, display advertising, content marketing, digital annual report, digital couponing, brand strategy, brand creation, brand revitalization, brand design, brand experience, employer branding, SEM, SEO, SEA, and more services.

Industry:
Marketing & Sales
Subindustry:
Adtech

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SB Score:419

Portworx is a cloud-native storage and data management company offering the industry’s first storage solution purpose-built for containers. With Portworx, they can manage any database or stateful service on any infrastructure using any container scheduler. It also enterprises depend on to reduce the cost and complexity of rapidly deploying containerized applications across multiple clouds and on-prem environments. Portworx creates a storage layer that allows developers to then access that data, no matter where it resides. The company solves the five most common problems DevOps teams encounter when running stateful services in production such as security, data automation, persistence, support, and high availability for multiple data stores and infrastructure. Portworx was founded in 2014 and is headquartered in Los Altos, CA, USA.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:418

DeSo is a layer-1 blockchain, like Bitcoin or Ethereum, that recently listed on Coinbase, has accumulated over 1.5 million accounts, and just crossed over $1B in volume transacted on-chain. DeSo is backed by Sequoia, Andreessen Horowitz, Social Capital, Coinbase Ventures, and many others. Our mission is to decentralize social media the same way Bitcoin and Ethereum are decentralizing the financial system. As a layer-1 blockchain, DeSo can be compared to other blockchains like Bitcoin, Ethereum, Solana, Avalanche, etc... However, DeSo has several major advantages over these platforms, the largest being that it is designed to power storage-heavy applications (like social applications and marketplaces). To put it in perspective, storing just a 200-character ""Tweet"" on Ethereum costs ~$80, and costs ~$0.25-$1.00+ on Solana, Avalanche, Polygon, and virtually all other smart contract chains. In contrast, it costs 1/1,000th of a penny on DeSo, which is why breakthrough apps like Diamond, DAODAO, Pearl, OpenProsper, NFTz, and Entre, now possible exclusively on DeSo. Today, social media is even more centralized than the financial industry was prior to the creation of Bitcoin. A handful of private entities effectively control public discourse, and earn monopoly profits off of content that they don't even create. Society’s answer to financial centralization was not to put Warren Buffett in charge of money, it was to use technology, namely Bitcoin, so we could have nobody in charge. We believe the same type of technology will cause this conclusion to ultimately play out in social. DeSo’s advantages make it capable of breaking this status quo for the first time, and bringing competition and innovation back to social in much the same way Bitcoin and Ethereum have done for our financial system. Moreover, if DeSo succeeds, we will no longer need individual ""dictators"" to set a homogenous moderation policy for hundreds of millions of people.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (United States)

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11th

Bioz
SB Score:412

Bioz is a cutting-edge AI search engine for life science research, helping scientists speed up their experiments. Empower your research with Bioz and discover new possibilities in the world of life science experimentation.

Industry:
Healthtech
Subindustry:
Life Sciences

National Rank (United States)

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Total amount:137

Top 74 Software & Data Startups in Los Altos for 2025

The top three Software & Data startups in Los Altos have raised more than USD 843M. Los Altos is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Software & Data industry.
SB Score:470

Bolster uses deep learning to stop counterfeit activity and protect top brands.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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SB Score:468

Prezent.ai provides an AI-driven platform designed to enhance communication productivity for teams and leaders. By leveraging machine learning, it improves the efficiency and effectiveness of business interactions, empowering users to communicate better and achieve their goals more effectively.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Regional Rank (North America)

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SB Score:443

Dwellsy is the top platform for finding rental properties in the U.S, offering the widest selection of listings. Discover your next home with ease on Dwellsy, the go-to marketplace for renters nationwide.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

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Total amount:74

Top 6 Fintech Startups in Los Altos for 2025

The top three Fintech startups in Los Altos have raised more than USD 211M. Los Altos is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Fintech industry.
SB Score:418

DeSo is a layer-1 blockchain, like Bitcoin or Ethereum, that recently listed on Coinbase, has accumulated over 1.5 million accounts, and just crossed over $1B in volume transacted on-chain. DeSo is backed by Sequoia, Andreessen Horowitz, Social Capital, Coinbase Ventures, and many others. Our mission is to decentralize social media the same way Bitcoin and Ethereum are decentralizing the financial system. As a layer-1 blockchain, DeSo can be compared to other blockchains like Bitcoin, Ethereum, Solana, Avalanche, etc... However, DeSo has several major advantages over these platforms, the largest being that it is designed to power storage-heavy applications (like social applications and marketplaces). To put it in perspective, storing just a 200-character ""Tweet"" on Ethereum costs ~$80, and costs ~$0.25-$1.00+ on Solana, Avalanche, Polygon, and virtually all other smart contract chains. In contrast, it costs 1/1,000th of a penny on DeSo, which is why breakthrough apps like Diamond, DAODAO, Pearl, OpenProsper, NFTz, and Entre, now possible exclusively on DeSo. Today, social media is even more centralized than the financial industry was prior to the creation of Bitcoin. A handful of private entities effectively control public discourse, and earn monopoly profits off of content that they don't even create. Society’s answer to financial centralization was not to put Warren Buffett in charge of money, it was to use technology, namely Bitcoin, so we could have nobody in charge. We believe the same type of technology will cause this conclusion to ultimately play out in social. DeSo’s advantages make it capable of breaking this status quo for the first time, and bringing competition and innovation back to social in much the same way Bitcoin and Ethereum have done for our financial system. Moreover, if DeSo succeeds, we will no longer need individual ""dictators"" to set a homogenous moderation policy for hundreds of millions of people.

Industry:
Fintech
Subindustry:
Blockchain

National Rank (United States)

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Regional Rank (North America)

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2nd

Byga
SB Score:376

Byga is an all-in-one sports platform for clubs, offering seamless integration and a wide range of features. Users can easily manage their club activities, schedules, and communication, all in one place.

Industry:
Fintech
Subindustry:
Payments

National Rank (United States)

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3rd

Meld
SB Score:343

Meld enables developers to create a comprehensive Multi-Vendor Fintech stack effortlessly. With just a few lines of code, they can access a diverse array of financial integrations across various domains, streamlining the development process and enhancing their applications with powerful financial solutions.

Industry:
Fintech
Subindustry:
Payments

National Rank (United States)

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Total amount:6

Top 21 Healthtech Startups in Los Altos for 2025

The top three Healthtech startups in Los Altos have raised more than USD 706M. Los Altos is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Healthtech industry.

1st

Bioz
SB Score:412

Bioz is a cutting-edge AI search engine for life science research, helping scientists speed up their experiments. Empower your research with Bioz and discover new possibilities in the world of life science experimentation.

Industry:
Healthtech
Subindustry:
Life Sciences

National Rank (United States)

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SB Score:394

Artera utilizes AI to create personalized cancer treatments, predicting effectiveness and assessing risks. Their tools support tailored clinical care, helping patients receive the most beneficial therapies.

Industry:
Healthtech
Subindustry:
Life Sciences

National Rank (United States)

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SB Score:388

AltruBio develops targeted antibody therapies for cancer and inflammatory diseases. Their focus is on creating innovative treatments to improve patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:21

Most Funded Startups in Los Altos for 2025

The top three most funded startups in Los Altos have raised total funding of more than USD 1.13B. Alto Neuroscience has 0.63% more funding than AltruBio.
SB Score:431

Alto Neuroscience is a clinical-stage biopharmaceutical company that integrates the biology of the patient into drug development to improve the lives of people with mental health conditions. Through its AI-enabled biomarker platform, Alto Neuroscience combines rich sources of information on patients’ brain activity and behavior to rapidly develop highly-effective medicines for targeted populations. Alto Neuroscience aims to replace today's trial-and-error clinical approach by aligning the right Alto drug with the right patient, redefining psychiatry at a time when the world needs it most.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:388

AltruBio develops targeted antibody therapies for cancer and inflammatory diseases. Their focus is on creating innovative treatments to improve patient outcomes.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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SB Score:388

Evommune uses tissue-based methods to drive innovation in medicine development. Their approach aims to speed up discoveries and bring about groundbreaking treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Total amount:137

Top Hiring Startups in Los Altos by Employee Number

The top three hiring startups in Los Altos have an median employee size that is between [101-250]
SB Score:328

The startup offers quick and affordable audio transcription services through a mix of crowd sourcing and automation. Users can easily record, share, and transcribe audio files with high quality results.

Industry:
Software & Data
Subindustry:
Software and Data-Other

National Rank (United States)

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Regional Rank (North America)

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SB Score:468

Prezent.ai provides an AI-driven platform designed to enhance communication productivity for teams and leaders. By leveraging machine learning, it improves the efficiency and effectiveness of business interactions, empowering users to communicate better and achieve their goals more effectively.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:443

Forward Networks, a startup founded and funded by SDN pioneers, aims to revolutionize network control software for more flexible, agile, and automated networks. Join us in driving industry-wide innovation towards a new era of networking.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:411

Evinced is a digital accessibility platform that assists companies in evaluating their online content for accessibility compliance. It helps businesses ensure that their digital assets are inclusive and user-friendly for all individuals.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Total amount:137

Explore the Startup Ecosystem of Los Altos

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
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1
37.971
00.00
00.00
00.00
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0
24th
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2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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