28 Top startups in Lancaster for April 2025

We rank Legacy Education, Simulations Plus and Immunomic Therapeutics in Lancaster along with 25 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Lancaster startup ecosystem ranks #414 globally and #122 in United States.

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Best Startups in Lancaster for 2025

SB Score:423

Legacy Education provides specialized programs in allied healthcare, veterinary, and business fields. Our courses offer comprehensive training to help individuals succeed in these industries. Join us to gain the skills and knowledge needed to excel in your career.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

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SB Score:393

Simulations Plus develops cutting-edge ADMET software for predicting drug absorption, distribution, metabolism, excretion, and toxicity. Revolutionizing drug development, their tools enable accurate and efficient evaluation of drug properties, guiding researchers in creating safer and more effective medications.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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SB Score:389

Immunomic Therapeutics creates vaccines using lysosomal associated membrane proteins. Their innovative approach aims to revolutionize immunotherapy.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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SB Score:325

A global benefits hub for all. Accessible to everyone, this platform offers a range of benefits in a user-friendly format. Join now to unlock endless opportunities and rewards.

Industry:
Fintech
Subindustry:
Insurance

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SB Score:310

Boostpoint® platform empowers Talent Acquisition teams to attract qualified leads and enhance their brand visibility on social media. Get all the tools needed to succeed in one place.

Industry:
Marketing & Sales
Subindustry:
Adtech

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SB Score:309

Energy Wall creates innovative energy recovery membranes that efficiently transfer heat and moisture. Their technology actively improves energy efficiency.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:291

MAKE/FILMS specializes in creating a wide range of video content, including identity films, TV commercials, training videos, documentaries, and more. Their expertise lies in producing engaging and professional visual media for a variety of purposes.

Industry:
Social & Leisure
Subindustry:
Entertainment

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SB Score:244

MedStatix provides a specialized patient survey platform that can be customized for any healthcare practice. This cloud-based tool helps providers gather feedback to improve patient experiences.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:215

CarthroniX specializes in innovative small-molecule therapies for cartilage diseases, including arthritis. Their groundbreaking treatments preserve, repair, and regenerate joint cartilage while effectively reducing inflammation, offering a comprehensive solution for those suffering from debilitating joint conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

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Specializing in company formation and registered agent services, this company helps startups establish their businesses efficiently. Offering expert guidance and support, they make the process seamless and stress-free.

Industry:
Software & Data
Subindustry:
Software and Data-Other

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SB Score:194

Blink revolutionizes online dating with a two-part matching process, moving beyond swiping and shallow conversations. By leveraging technology, Blink creates meaningful connections and a high-quality dating experience. Say goodbye to endless swiping and hello to a new way of finding love.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:28

Top 9 Software & Data Startups in Lancaster for 2025

The top three Software & Data startups in Lancaster have raised more than USD 2.46M. Lancaster startup ecosystem ranks #419 globally for the Software & Data industry.
SB Score:244

MedStatix provides a specialized patient survey platform that can be customized for any healthcare practice. This cloud-based tool helps providers gather feedback to improve patient experiences.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Specializing in company formation and registered agent services, this company helps startups establish their businesses efficiently. Offering expert guidance and support, they make the process seamless and stress-free.

Industry:
Software & Data
Subindustry:
Software and Data-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:194

Blink revolutionizes online dating with a two-part matching process, moving beyond swiping and shallow conversations. By leveraging technology, Blink creates meaningful connections and a high-quality dating experience. Say goodbye to endless swiping and hello to a new way of finding love.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:9

Top 3 Ecommerce & Retail Startups in Lancaster for 2025

Lancaster startup ecosystem ranks #359 globally for the Ecommerce & Retail industry.
SB Score:81

Schedule Engine revolutionizes home services contractors' customer experience with modern technology. Streamline and enhance scheduling processes to provide a seamless and efficient service.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

National Rank (United States)

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Regional Rank (North America)

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SB Score:33

Specializing in purchasing distressed properties in the Antelope Valley, we renovate and sell to first-time homebuyers. Our mission is to provide affordable housing options while revitalizing the community.

Industry:
Ecommerce & Retail
Subindustry:
Proptech

National Rank (United States)

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Regional Rank (North America)

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SB Score:32

Specializing in online marketing optimization, this startup drives profitable revenue growth for businesses. Their expert strategies and tactics help businesses achieve success in the digital landscape.

Industry:
Ecommerce & Retail
Subindustry:
Social Commerce

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:3

Top 3 Edtech Startups in Lancaster for 2025

The top three Edtech startups in Lancaster have raised more than USD 1.37M. Lancaster startup ecosystem ranks #311 globally for the Edtech industry.
SB Score:423

Legacy Education provides specialized programs in allied healthcare, veterinary, and business fields. Our courses offer comprehensive training to help individuals succeed in these industries. Join us to gain the skills and knowledge needed to excel in your career.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:23

BuildingIt provides precise location data and powerful mapping tools for tracking digital assets. Their map design tools and collaborative functionality make maps dynamic and productive.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:3

Most Funded Startups in Lancaster for 2025

The top three most funded startups in Lancaster have raised total funding of more than USD 241M. Immunomic Therapeutics has 22.19% more funding than BeneFix.
SB Score:389

Immunomic Therapeutics creates vaccines using lysosomal associated membrane proteins. Their innovative approach aims to revolutionize immunotherapy.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:325

A global benefits hub for all. Accessible to everyone, this platform offers a range of benefits in a user-friendly format. Join now to unlock endless opportunities and rewards.

Industry:
Fintech
Subindustry:
Insurance

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:309

Energy Wall creates innovative energy recovery membranes that efficiently transfer heat and moisture. Their technology actively improves energy efficiency.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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Total amount:28

Top Hiring Startups in Lancaster by Employee Number

The top three hiring startups in Lancaster have an median employee size that is between [51-100]
SB Score:423

Legacy Education provides specialized programs in allied healthcare, veterinary, and business fields. Our courses offer comprehensive training to help individuals succeed in these industries. Join us to gain the skills and knowledge needed to excel in your career.

Industry:
Edtech
Subindustry:
Education-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:393

Simulations Plus develops cutting-edge ADMET software for predicting drug absorption, distribution, metabolism, excretion, and toxicity. Revolutionizing drug development, their tools enable accurate and efficient evaluation of drug properties, guiding researchers in creating safer and more effective medications.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:389

Immunomic Therapeutics creates vaccines using lysosomal associated membrane proteins. Their innovative approach aims to revolutionize immunotherapy.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:325

A global benefits hub for all. Accessible to everyone, this platform offers a range of benefits in a user-friendly format. Join now to unlock endless opportunities and rewards.

Industry:
Fintech
Subindustry:
Insurance

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:28

Explore the Startup Ecosystem of Lancaster

National Rank

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Regional Rank

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136th

4

Global Rank

(WorldWide)

414th

30

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
7th
+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
-
1
37.971
00.00
00.00
00.00
9th
0
24th
-
2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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