18 Top startups in Laguna Hills for April 2025

We rank Centercode, Prelude Corp and Adagio Medical in Laguna Hills along with 15 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Laguna Hills is part of Los Angeles Area startup ecosystem which ranks #4 globally and #3 in North America.

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Best Startups in Laguna Hills for 2025

SB Score:432

Centercode offers a SaaS platform for Alpha, Beta, and Delta Tests. They provide services for Customer Validation, making it easy for companies to gather feedback from users.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:394

Prelude Corp offers personalized tools to manage early stage breast cancer with the DCIS test, providing actionable insights for tailored treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:340

Adagio Medical develops innovative treatments for cardiovascular conditions, aiming to improve patient outcomes. Their focus is on research and development in the field of cardiology to provide effective solutions for heart-related diseases.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:337

Arthrosi Therapeutics, a Laguna Hills-based biotech startup established in 2017, specializes in innovative drug research and development. Their focus is on creating cutting-edge therapies.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:296

Amberstone Biosciences specializes in developing novel immunotherapies by leveraging innovative technologies and strategic partnerships. The company targets complex challenges that demand unique modes of action and specific functional properties, which are often overlooked by traditional approaches.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:288

Eyedaptic offers a cutting-edge wearable device combined with advanced vision-enhancing software that replicates natural sight. This innovative solution provides comfort and clarity for individuals with vision impairments, empowering them to experience the world with greater ease and confidence.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

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SB Score:283

Metronom Health offers innovative glucose monitoring systems for effective diabetes management. Their continuous monitoring technology provides real-time data to help users track and control their glucose levels effortlessly.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:269

WiSilica’s platform offers a smart, flexible solution for converging infrastructure seamlessly.

Industry:
Marketing & Sales
Subindustry:
Marketing & Sales-Other

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SB Score:255

RepeaterStore is a top distributor of cellular repeaters, offering solutions for cell phone signal issues to customers in the US and Canada. With clients like Apple, NASA, and the FBI, they specialize in providing cutting-edge technology to improve connectivity for individuals and businesses.

Industry:
Ecommerce & Retail
Subindustry:
Retail

National Rank (United States)

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Total amount:18

Top 3 Software & Data Startups in Laguna Hills for 2025

The top three Software & Data startups in Laguna Hills have raised more than USD 9.5M. Laguna Hills is part of Los Angeles Area startup ecosystem which ranks #6 globally for the Software & Data industry.
SB Score:432

Centercode offers a SaaS platform for Alpha, Beta, and Delta Tests. They provide services for Customer Validation, making it easy for companies to gather feedback from users.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:140

Exitus Elite is an online marketing and training system that combines the Internet's reach with the earning potential of digital products. Their products offer a unique opportunity to leverage the power of the internet for income generation.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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Connect is a business chat app that brings all your people and communication in one place. Unlike other chat apps, Connect empowers businesses to easily communicate and collaborate in different department and team structures across your business.

Industry:
Software & Data
Subindustry:
Software and Data-Other

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Total amount:3

Top 2 Ecommerce & Retail Startups in Laguna Hills for 2025

Laguna Hills is part of Los Angeles Area startup ecosystem which ranks #3 globally for the Ecommerce & Retail industry.
SB Score:255

RepeaterStore is a top distributor of cellular repeaters, offering solutions for cell phone signal issues to customers in the US and Canada. With clients like Apple, NASA, and the FBI, they specialize in providing cutting-edge technology to improve connectivity for individuals and businesses.

Industry:
Ecommerce & Retail
Subindustry:
Retail

National Rank (United States)

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SB Score:71

SolarCo Energy specializes in renewable energy solutions, focusing on solar biomass technology. Their innovative systems harness solar energy to generate electricity and heat water, providing efficient and sustainable energy solutions for homes and businesses.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

National Rank (United States)

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Total amount:2

Most Funded Startups in Laguna Hills for 2025

The top three most funded startups in Laguna Hills have raised total funding of more than USD 456M. Arthrosi Therapeutics has 5.38% more funding than Adagio Medical.
SB Score:337

Arthrosi Therapeutics, a Laguna Hills-based biotech startup established in 2017, specializes in innovative drug research and development. Their focus is on creating cutting-edge therapies.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:340

Adagio Medical develops innovative treatments for cardiovascular conditions, aiming to improve patient outcomes. Their focus is on research and development in the field of cardiology to provide effective solutions for heart-related diseases.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:18

Top Hiring Startups in Laguna Hills by Employee Number

The top three hiring startups in Laguna Hills have an median employee size that is between [51-100]
SB Score:127

Wallaby Medical is an innovative manufacturer specializing in Avenir coil systems and advanced medical devices designed for effective stroke treatment. With a commitment to enhancing patient outcomes, Wallaby Medical combines cutting-edge technology and expertise to deliver reliable solutions in the medical field.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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SB Score:432

Centercode offers a SaaS platform for Alpha, Beta, and Delta Tests. They provide services for Customer Validation, making it easy for companies to gather feedback from users.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:269

WiSilica’s platform offers a smart, flexible solution for converging infrastructure seamlessly.

Industry:
Marketing & Sales
Subindustry:
Marketing & Sales-Other

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:394

Prelude Corp offers personalized tools to manage early stage breast cancer with the DCIS test, providing actionable insights for tailored treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:18

Explore the Startup Ecosystem of Laguna Hills

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

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Quantity Score
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Quality Score
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Business Score
1st
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1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
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0
5th
0
109.679
00.00
00.00
00.00
5th
0
12th
0
52.052
00.00
00.00
00.00
6th
0
15th
0
42.256
00.00
00.00
00.00
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+
1
17th
+
4
41.259
00.00
00.00
00.00
8th
-
1
19th
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1
37.971
00.00
00.00
00.00
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0
24th
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2
34.098
00.00
00.00
00.00
10th
0
25th
+
1
33.768
00.00
00.00
00.00
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