40 Top startups in La Jolla for January 2025

We rank Resilience, Aira and The Good Face Project in La Jolla along with 37 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. La Jolla is part of San Diego which ranks #24 globally and #10 in North America.

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Best Startups in La Jolla for 2025

SB Score:650

Resilience offers comprehensive biopharmaceutical manufacturing and development solutions, committed to expanding access to complex medicines while safeguarding supply chains from disruptions. Founded in 2020 in La Jolla, California, the company is dedicated to enhancing the reliability and accessibility of critical biopharmaceuticals.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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2nd

Aira
SB Score:453

Aira offers on-demand visual interpretation services for the blind and low vision community, making the world more accessible. Described as a Godsend by The New York Times, Aira's mission is to provide remote assistance anytime, anywhere.

Industry:
Hardware & IoT
Subindustry:
Hardware & IoT-Other

National Rank (United States)

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SB Score:429

Good Face Project has created a groundbreaking AI-driven innovation hub for beauty and personal care, utilizing the world's largest proprietary cosmetic ingredients ontology. This science-backed platform empowers users to discover personalized product recommendations and enhance their understanding of cosmetic ingredients for more informed purchasing decisions.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

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Regional Rank (North America)

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SB Score:396

Enlaza Therapeutics, a biotech research startup based in La Jolla, CA, was established in 2020. Specializing in biotechnology, the company focuses on cutting-edge research and development.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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SB Score:379

Genomic Life empowers policyholders and employees globally by providing innovative genomic products through trusted employee benefit brokers. By advancing genomic medicine and proactive health, it aims to make transformative healthcare accessible to everyone, revolutionizing the way individuals approach their health and wellness.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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SB Score:339

Arialys Therapeutics is a pre-clinical stage company dedicated to exploring the role of auto-antibodies in neuroscience. By investigating how the immune system influences central nervous system health, disease progression, and treatment strategies, Arialys aims to pave the way for innovative therapeutic solutions in neuroimmunology.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:333

Rampart Bioscience develops innovative gene therapies aimed at delivering lasting treatments for various diseases. Their proprietary development and delivery platforms create optimized therapeutics in a reversible, non-viral format, ensuring effective and safe solutions for patients in need of advanced medical care.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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SB Score:332

Genome Insight develops a comprehensive genome sequence analysis and interpretation platform. By delivering precise insights from full-length genomic data, it empowers clients to effectively leverage this information to enhance their operations and drive informed decision-making.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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9th

Tr1x
SB Score:332

Tr1x specializes in developing innovative cellular therapies aimed at effectively treating autoimmune disorders. By harnessing the power of cellular technology, Tr1x strives to provide groundbreaking solutions that improve patient outcomes and enhance quality of life for those affected by these challenging conditions.

Industry:
Ecommerce & Retail
Subindustry:
Retail

National Rank (United States)

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Regional Rank (North America)

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SB Score:319

Model Medicines leverages human expertise and advanced AI to expedite the development of transformative drugs at scale, enhancing the efficiency and effectiveness of the drug discovery process.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

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11th

XNow
SB Score:307

XNow is an innovative online platform that offers proprietary eligibility verification technologies, enabling users to easily determine their qualification for exclusive discounts on travel, hotels, car rentals, and event tickets, including major league sports, concerts, festivals, theme parks, and more.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:40

Top 10 Healthtech Startups in La Jolla for 2025

The top three Healthtech startups in La Jolla have raised more than USD 2.37B. La Jolla is part of San Diego which ranks #5 globally for the Healthtech industry.
SB Score:650

Resilience offers comprehensive biopharmaceutical manufacturing and development solutions, committed to expanding access to complex medicines while safeguarding supply chains from disruptions. Founded in 2020 in La Jolla, California, the company is dedicated to enhancing the reliability and accessibility of critical biopharmaceuticals.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:396

Enlaza Therapeutics, a biotech research startup based in La Jolla, CA, was established in 2020. Specializing in biotechnology, the company focuses on cutting-edge research and development.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:339

Arialys Therapeutics is a pre-clinical stage company dedicated to exploring the role of auto-antibodies in neuroscience. By investigating how the immune system influences central nervous system health, disease progression, and treatment strategies, Arialys aims to pave the way for innovative therapeutic solutions in neuroimmunology.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:10

Top 12 Software & Data Startups in La Jolla for 2025

The top three Software & Data startups in La Jolla have raised more than USD 36.1M. La Jolla is part of San Diego which ranks #20 globally for the Software & Data industry.
SB Score:429

Good Face Project has created a groundbreaking AI-driven innovation hub for beauty and personal care, utilizing the world's largest proprietary cosmetic ingredients ontology. This science-backed platform empowers users to discover personalized product recommendations and enhance their understanding of cosmetic ingredients for more informed purchasing decisions.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:379

Genomic Life empowers policyholders and employees globally by providing innovative genomic products through trusted employee benefit brokers. By advancing genomic medicine and proactive health, it aims to make transformative healthcare accessible to everyone, revolutionizing the way individuals approach their health and wellness.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:319

Model Medicines leverages human expertise and advanced AI to expedite the development of transformative drugs at scale, enhancing the efficiency and effectiveness of the drug discovery process.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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Total amount:12

Top 1 Marketing & Sales Startups in La Jolla for 2025

The top three Marketing & Sales startups in La Jolla have raised more than USD 366K. La Jolla is part of San Diego which ranks #12 globally for the Marketing & Sales industry.
SB Score:223

Novelty Media's owned-and-operated properties celebrate and engage with the vibrant world of internet culture, showcasing the best of online trends and communities. Through innovative content and interactive experiences, they actively participate in shaping and honoring the digital landscape.

Industry:
Marketing & Sales
Subindustry:
Adtech

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:1

Most Funded Startups in La Jolla for 2025

The top three most funded startups in La Jolla have raised total funding of more than USD 2.37B. Resilience has 11.86% more funding than Enlaza Therapeutics.
SB Score:650

Resilience offers comprehensive biopharmaceutical manufacturing and development solutions, committed to expanding access to complex medicines while safeguarding supply chains from disruptions. Founded in 2020 in La Jolla, California, the company is dedicated to enhancing the reliability and accessibility of critical biopharmaceuticals.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:396

Enlaza Therapeutics, a biotech research startup based in La Jolla, CA, was established in 2020. Specializing in biotechnology, the company focuses on cutting-edge research and development.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:333

Rampart Bioscience develops innovative gene therapies aimed at delivering lasting treatments for various diseases. Their proprietary development and delivery platforms create optimized therapeutics in a reversible, non-viral format, ensuring effective and safe solutions for patients in need of advanced medical care.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:40

Top Hiring Startups in La Jolla by Employee Number

The top three hiring startups in La Jolla have an median employee size that is between [101-250]
SB Score:650

Resilience offers comprehensive biopharmaceutical manufacturing and development solutions, committed to expanding access to complex medicines while safeguarding supply chains from disruptions. Founded in 2020 in La Jolla, California, the company is dedicated to enhancing the reliability and accessibility of critical biopharmaceuticals.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:137

Genesis Digital offers Karta, an online business platform with marketing and sales tools to help businesses grow. Founded in 2013 and headquartered in La Jolla, California, they provide SaaS eCommerce solutions to a growing market of innovators.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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3rd

Aira
SB Score:453

Aira offers on-demand visual interpretation services for the blind and low vision community, making the world more accessible. Described as a Godsend by The New York Times, Aira's mission is to provide remote assistance anytime, anywhere.

Industry:
Hardware & IoT
Subindustry:
Hardware & IoT-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:379

Genomic Life empowers policyholders and employees globally by providing innovative genomic products through trusted employee benefit brokers. By advancing genomic medicine and proactive health, it aims to make transformative healthcare accessible to everyone, revolutionizing the way individuals approach their health and wellness.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:40

Explore the Startup Ecosystem of La Jolla

National Rank

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9th

0

Regional Rank

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10th

1

Global Rank

(WorldWide)

24th

2

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710.966
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251.377
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121.937
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109.679
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