50 Top startups in Hayward for April 2025

We rank RefleXion Medical, Moximed and Alamar Biosciences in Hayward along with 47 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Hayward is part of San Francisco Bay startup ecosystem which ranks #1 globally and #1 in North America.

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Top Unicorn Startups in Hayward for 2025

Eikon Therapeutics is the only unicorn in Hayward raising more than USD 3.2B. It is the undefined ranked unicorn in North America.
SB Score:499

This company uses cutting-edge technology to develop new treatments for deadly diseases by combining biology, engineering, and chemistry.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:1

Best Startups in Hayward for 2025

SB Score:473

RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:428

Moximed elevates osteoarthritis patient care by exploring innovative joint treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:422

Alamar Biosciences pioneers early detection and treatment tech for cancer and diseases. Their innovations aim to catch illnesses at their earliest stages, enhancing chances for successful treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

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Octillion Power Systems offers cutting-edge lithium-ion batteries for industrial and vehicle use. Their advanced technology provides reliable and efficient power solutions for a variety of applications.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:408

Ripcord is a company that creates a robotic digitizing platform for paperless document management. The company creates a digital twin of information using sensors and software automation, as well as document scanning and accurate recognition, as well as vision-guided robots, artificial intelligence, and machine learning to capture, enrich, and organize important content, allowing clients to streamline their business processes with high speed, quality, and accuracy.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:398

Kite Hill produces delicious cheeses, cream cheeses, and yogurts crafted from almond milk. Experience their dairy-free, plant-based products that provide a flavorful and healthy alternative for those looking to enjoy dairy-free options.

Industry:
Foodtech
Subindustry:
Agtech

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SB Score:397

Halio is revolutionizing glass technology with adaptive, dynamic solutions for commercial, residential, and automotive use. Experience the future of glass with customizable tint levels at the touch of a button.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:388

Verdant's Model B Smart Sprayer enables growers to reduce labor costs by 50% or more and decrease input costs by 96%. The Model B weeds and thins all types of crops (including high-density and conventional), in all types of fields (including organic and no-till), day or night. Our proprietary Bullseye targeting technology combined with the Model B's Pinpoint Spray System unlocks new profitability through micro-fertilization and nutrient delivery leading to substantial yield increases. Verdant helps growers of all sizes produce more food, more efficiently.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:379

ConXtech provides innovative construction technology solutions for commercial and residential projects. Streamlining processes and enhancing efficiency, they offer a range of products to revolutionize the housing industry.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:364

Pact Pharma develops personalized T cell therapies to target and eliminate solid tumors effectively.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:363

Spotlight Therapeutics develops targeted biologics for precise gene editing in specific cell types. Their innovative approach aims to revolutionize the field of biotechnology by creating therapies tailored to individual patient needs.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Total amount:50

Top 4 Software & Data Startups in Hayward for 2025

The top three Software & Data startups in Hayward have raised more than USD 143M. Hayward is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Software & Data industry.
SB Score:408

Ripcord is a company that creates a robotic digitizing platform for paperless document management. The company creates a digital twin of information using sensors and software automation, as well as document scanning and accurate recognition, as well as vision-guided robots, artificial intelligence, and machine learning to capture, enrich, and organize important content, allowing clients to streamline their business processes with high speed, quality, and accuracy.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:286

Renovai revolutionizes interior design with AI technology, offering a personalized shopping experience for furniture retailers.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:155

Respond Fast™ simplifies responding to offers through smart speakers. Users can easily engage with promotions using voice commands, making it convenient and efficient.

Industry:
Software & Data
Subindustry:
Software

National Rank (United States)

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Total amount:4

Top 17 Healthtech Startups in Hayward for 2025

The top three Healthtech startups in Hayward have raised more than USD 1.43B. Hayward is part of San Francisco Bay startup ecosystem which ranks #1 globally for the Healthtech industry.
SB Score:473

RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:428

Moximed elevates osteoarthritis patient care by exploring innovative joint treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:422

Alamar Biosciences pioneers early detection and treatment tech for cancer and diseases. Their innovations aim to catch illnesses at their earliest stages, enhancing chances for successful treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:17

Most Funded Startups in Hayward for 2025

The top three most funded startups in Hayward have raised total funding of more than USD 1.64B. RefleXion Medical has 0.31% more funding than Halio.
SB Score:473

RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:397

Halio is revolutionizing glass technology with adaptive, dynamic solutions for commercial, residential, and automotive use. Experience the future of glass with customizable tint levels at the touch of a button.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:428

Moximed elevates osteoarthritis patient care by exploring innovative joint treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:50

Top Hiring Startups in Hayward by Employee Number

The top three hiring startups in Hayward have an median employee size that is between [1001-5000]

Octillion Power Systems offers cutting-edge lithium-ion batteries for industrial and vehicle use. Their advanced technology provides reliable and efficient power solutions for a variety of applications.

Industry:
Energy & Environment
Subindustry:
Energy

National Rank (United States)

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Regional Rank (North America)

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Ultra Clean Holdings, Inc. specializes in providing critical subsystems, components, ultra-high purity cleaning services, and analytical services for the semiconductor industry. Their expertise helps semiconductor companies maintain high standards of cleanliness and performance.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

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Regional Rank (North America)

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SB Score:473

RefleXion is developing the first biology-guided radiotherapy system, a significant change in strategy from single tumor therapy to the ability to one day treat multiple tumors in the same treatment session in cancers that have metastasized. Currently, the RefleXion X1 machine is cleared for the delivery of stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS) and intensity modulated radiotherapy (IMRT). The company is also developing BgRT, which incorporates positron-emission tomography (PET) imaging data to enable tumors to continuously signal their location. The BgRT technology will synchronize these data with the linear accelerator to direct radiotherapy to tumors with subsecond latency.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:397

Halio is revolutionizing glass technology with adaptive, dynamic solutions for commercial, residential, and automotive use. Experience the future of glass with customizable tint levels at the touch of a button.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:50

Explore the Startup Ecosystem of Hayward

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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3rd
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121.937
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109.679
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