23 Top startups in Frederick for January 2025

We rank EDUsys Global, Fugue and RoosterBio in Frederick along with 20 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Frederick ranks #497 globally and #144 in United States.

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Best Startups in Frederick for 2025

SB Score:362

EDUsys Global offers internationally recognized education courses, endorsed by prestigious institutions. Their training programs are designed to enhance skills and knowledge for individuals seeking global recognition in the field of education.

Industry:
Social & Leisure
Subindustry:
Sports

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SB Score:343

Fugue keeps cloud infrastructure compliant with security policies, ensuring continuous adherence.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:341

RoosterBio provides affordable, high volume living cellular materials like Mesenchymal Stem Cells, making it easier and cheaper to incorporate biologics into various technologies. Their products simplify the process and accelerate the development of cell-based innovations for the future.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:339

A decentralized Oracle for DeFi, providing secure and reliable data feeds for decentralized finance applications.

Industry:
Fintech
Subindustry:
Cryptocurrency

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SB Score:329

Theradaptive is revolutionizing protein therapeutics by utilizing its innovative platform to transform any protein into a targeted binding variant. This technology enables ultra-precise delivery and retention of therapeutics at specific sites in the body, enhancing treatment efficacy and minimizing side effects.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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SB Score:326

Nanobiofab accelerates nanomaterial research and development by offering innovative nanoprinting technologies and solutions. Additionally, it provides advanced artificial intelligence sensors designed for telemedicine and personalized healthcare, enhancing the efficiency and effectiveness of medical services.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:326

Akonni Biosystems develops genetic testing devices for accurate and quick analysis. Their innovative technology provides precise results, making genetic testing accessible and efficient for various applications.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:315

KnowledgeNet.ai delivers innovative knowledge intelligence solutions that transform organizational collaboration. By harnessing the power of intellectual capital, it enables businesses to connect, share, and utilize their collective expertise more effectively, driving greater efficiency and fostering a culture of continuous learning.

Industry:
General
Subindustry:
Select an Industry first...

National Rank (United States)

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SB Score:312

BioFactura is a biopharmaceutical company specializing in research and manufacturing. They develop innovative medicines and treatments to improve healthcare.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:310

FESCO Energy provides reliable and durable electricity solutions. Their services ensure a stable and secure power supply for all customers.

Industry:
Energy & Environment
Subindustry:
Energy

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SB Score:290

Veralox Therapeutics creates small molecule drugs targeting thrombosis and type 1 diabetes. Their innovative therapies address the root causes of these conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Regional Rank (North America)

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Total amount:23

Top 10 Healthtech Startups in Frederick for 2025

The top three Healthtech startups in Frederick have raised more than USD 179M. Frederick ranks #206 globally for the Healthtech industry.
SB Score:341

RoosterBio provides affordable, high volume living cellular materials like Mesenchymal Stem Cells, making it easier and cheaper to incorporate biologics into various technologies. Their products simplify the process and accelerate the development of cell-based innovations for the future.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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SB Score:326

Akonni Biosystems develops genetic testing devices for accurate and quick analysis. Their innovative technology provides precise results, making genetic testing accessible and efficient for various applications.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:312

BioFactura is a biopharmaceutical company specializing in research and manufacturing. They develop innovative medicines and treatments to improve healthcare.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:10

Top 5 Software & Data Startups in Frederick for 2025

The top three Software & Data startups in Frederick have raised more than USD 120M. Frederick ranks among the top 10 locations in the world for startups in Software & Data, holding the 2nd position.
SB Score:343

Fugue keeps cloud infrastructure compliant with security policies, ensuring continuous adherence.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:329

Theradaptive is revolutionizing protein therapeutics by utilizing its innovative platform to transform any protein into a targeted binding variant. This technology enables ultra-precise delivery and retention of therapeutics at specific sites in the body, enhancing treatment efficacy and minimizing side effects.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:220

Datakwip's software identifies energy-saving opportunities in buildings, helping users reduce costs and environmental impact.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

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Regional Rank (North America)

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Total amount:5

Top 3 Hardware & IoT Startups in Frederick for 2025

The top three Hardware & IoT startups in Frederick have raised more than USD 1.52M. Frederick ranks among the top 10 locations in the world for startups in Hardware & IoT, holding the 3rd position.
SB Score:326

Nanobiofab accelerates nanomaterial research and development by offering innovative nanoprinting technologies and solutions. Additionally, it provides advanced artificial intelligence sensors designed for telemedicine and personalized healthcare, enhancing the efficiency and effectiveness of medical services.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

0

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SB Score:286

EXOsecure is a cybersecurity service harnessing the power of crowd, cloud, and community to protect your digital assets. With a focus on clarity and engagement, EXOsecure offers advanced protection in a concise and user-friendly manner.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

0

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Regional Rank (North America)

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Matet's Kitchen is a vibrant Filipino food brand that celebrates the rich flavors and traditions of the Philippines. Specializing in authentic recipes and high-quality ingredients, it offers a delightful culinary experience that brings the taste of home to every meal, connecting food lovers with the heart of Filipino cuisine.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:3

Most Funded Startups in Frederick for 2025

The top three most funded startups in Frederick have raised total funding of more than USD 218M. Fugue has 0.12% more funding than BioFactura.
SB Score:343

Fugue keeps cloud infrastructure compliant with security policies, ensuring continuous adherence.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:312

BioFactura is a biopharmaceutical company specializing in research and manufacturing. They develop innovative medicines and treatments to improve healthcare.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:326

Akonni Biosystems develops genetic testing devices for accurate and quick analysis. Their innovative technology provides precise results, making genetic testing accessible and efficient for various applications.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:23

Top Hiring Startups in Frederick by Employee Number

The top three hiring startups in Frederick have an median employee size that is between [51-100]
SB Score:326

Nanobiofab accelerates nanomaterial research and development by offering innovative nanoprinting technologies and solutions. Additionally, it provides advanced artificial intelligence sensors designed for telemedicine and personalized healthcare, enhancing the efficiency and effectiveness of medical services.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:362

EDUsys Global offers internationally recognized education courses, endorsed by prestigious institutions. Their training programs are designed to enhance skills and knowledge for individuals seeking global recognition in the field of education.

Industry:
Social & Leisure
Subindustry:
Sports

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:329

Theradaptive is revolutionizing protein therapeutics by utilizing its innovative platform to transform any protein into a targeted binding variant. This technology enables ultra-precise delivery and retention of therapeutics at specific sites in the body, enhancing treatment efficacy and minimizing side effects.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:326

Akonni Biosystems develops genetic testing devices for accurate and quick analysis. Their innovative technology provides precise results, making genetic testing accessible and efficient for various applications.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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Total amount:23

Explore the Startup Ecosystem of Frederick

National Rank

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144th

14

Regional Rank

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163rd

18

Global Rank

(WorldWide)

497th

70

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Quantity Score
Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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109.679
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