18 Top startups in Framingham for January 2025

We rank Re:Build, Variantyx and Trilio in Framingham along with 15 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Framingham is part of Boston Area which ranks #5 globally and #4 in North America.

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Top Unicorn Startups in Framingham for 2025

Alzheon is the only unicorn in Framingham raising more than USD 1.31B. It is the undefined ranked unicorn in North America.
SB Score:411

Alzheon's ALZ-801 is the leading oral treatment being tested for Alzheimer's disease, offering potential disease-modifying benefits. It is the only product in late-stage trials, providing hope for those affected by this devastating condition.

Industry:
Healthtech
Subindustry:
Health Care

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Total amount:1

Best Startups in Framingham for 2025

SB Score:491

Re:Build is an innovative industrial manufacturing company that seamlessly combines advanced technologies with traditional manufacturing processes, enhancing efficiency and quality. By leveraging cutting-edge solutions, Re:Build transforms the manufacturing landscape, driving productivity and enabling businesses to thrive in a competitive market.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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SB Score:442

Variantyx provides cutting-edge genomic diagnostic services using whole genome sequencing. Their advanced products offer comprehensive genetic analysis to help individuals and healthcare professionals make informed decisions about health and treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:407

Revolutionize data protection for Kubernetes, OpenStack, and virtualization with our cloud-native solution. Secure your data seamlessly and efficiently across platforms.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:377

Beamable helps game developers enhance their games with social, commerce, and content management tools. With Beamable, developers can easily add features to engage players and monetize their games effectively.

Industry:
Social & Leisure
Subindustry:
Communities

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SB Score:350

Revolutionize coatings with our nano-technology based formulas, free from harmful fluorochemicals (NO PFC, PFOA, PFOS or PFAS). Experience state-of-the-art protection without compromise.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

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SB Score:345

Correlsense provides powerful software that identifies issues with app performance, preventing downtime and disruptions for businesses. Their enterprise solution detects and resolves problems quickly, ensuring smooth operation and optimal user experience.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:313

Raven360 offers a sales readiness platform that provides sales teams with current content, training, and coaching to enhance their performance.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:300

BERG LLC supplies pharmaceutical and biotechnology products to medical professionals. Specializing in innovative solutions, they offer cutting-edge treatments for various health conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

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10th

Vizium
SB Score:281

Vizium is an e-marketing and customer relationship consulting firm that helps businesses enhance their online presence and customer engagement.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:279

Utilizing cutting-edge technology, this online test prep company specializes in GRE test prep and MBA consulting. Tailored to individual needs, their services optimize and personalize the studying experience for maximum success.

Industry:
Edtech
Subindustry:
Education-Other

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Total amount:18

Top 6 Healthtech Startups in Framingham for 2025

The top three Healthtech startups in Framingham have raised more than USD 128M. Framingham is part of Boston Area which ranks #2 globally for the Healthtech industry.
SB Score:442

Variantyx provides cutting-edge genomic diagnostic services using whole genome sequencing. Their advanced products offer comprehensive genetic analysis to help individuals and healthcare professionals make informed decisions about health and treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:300

BERG LLC supplies pharmaceutical and biotechnology products to medical professionals. Specializing in innovative solutions, they offer cutting-edge treatments for various health conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Total amount:6

Top 4 Software & Data Startups in Framingham for 2025

The top three Software & Data startups in Framingham have raised more than USD 67.4M. Framingham is part of Boston Area which ranks #5 globally for the Software & Data industry.
SB Score:407

Revolutionize data protection for Kubernetes, OpenStack, and virtualization with our cloud-native solution. Secure your data seamlessly and efficiently across platforms.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:345

Correlsense provides powerful software that identifies issues with app performance, preventing downtime and disruptions for businesses. Their enterprise solution detects and resolves problems quickly, ensuring smooth operation and optimal user experience.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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SB Score:313

Raven360 offers a sales readiness platform that provides sales teams with current content, training, and coaching to enhance their performance.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

0

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Total amount:4

Top 1 Ecommerce & Retail Startups in Framingham for 2025

The top three Ecommerce & Retail startups in Framingham have raised more than USD 14M. Framingham is part of Boston Area which ranks #11 globally for the Ecommerce & Retail industry.
SB Score:350

Revolutionize coatings with our nano-technology based formulas, free from harmful fluorochemicals (NO PFC, PFOA, PFOS or PFAS). Experience state-of-the-art protection without compromise.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

National Rank (United States)

0

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Regional Rank (North America)

0

View

Global Rank (WorldWide)

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Total amount:1

Most Funded Startups in Framingham for 2025

The top three most funded startups in Framingham have raised total funding of more than USD 385M. Re:Build has 1.00% more funding than Variantyx.
SB Score:491

Re:Build is an innovative industrial manufacturing company that seamlessly combines advanced technologies with traditional manufacturing processes, enhancing efficiency and quality. By leveraging cutting-edge solutions, Re:Build transforms the manufacturing landscape, driving productivity and enabling businesses to thrive in a competitive market.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:442

Variantyx provides cutting-edge genomic diagnostic services using whole genome sequencing. Their advanced products offer comprehensive genetic analysis to help individuals and healthcare professionals make informed decisions about health and treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:407

Revolutionize data protection for Kubernetes, OpenStack, and virtualization with our cloud-native solution. Secure your data seamlessly and efficiently across platforms.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:18

Top Hiring Startups in Framingham by Employee Number

The top three hiring startups in Framingham have an median employee size that is between [251-500]
SB Score:491

Re:Build is an innovative industrial manufacturing company that seamlessly combines advanced technologies with traditional manufacturing processes, enhancing efficiency and quality. By leveraging cutting-edge solutions, Re:Build transforms the manufacturing landscape, driving productivity and enabling businesses to thrive in a competitive market.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:300

BERG LLC supplies pharmaceutical and biotechnology products to medical professionals. Specializing in innovative solutions, they offer cutting-edge treatments for various health conditions.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:442

Variantyx provides cutting-edge genomic diagnostic services using whole genome sequencing. Their advanced products offer comprehensive genetic analysis to help individuals and healthcare professionals make informed decisions about health and treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:345

Correlsense provides powerful software that identifies issues with app performance, preventing downtime and disruptions for businesses. Their enterprise solution detects and resolves problems quickly, ensuring smooth operation and optimal user experience.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:18

Explore the Startup Ecosystem of Framingham

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Top Cities for Startups in United States - Ranked by StartupBlink
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2024 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
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1st
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710.966
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2nd
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251.377
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3rd
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4th
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121.937
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4th
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5th
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109.679
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