334 Top startups in Baltimore for April 2025

We rank Enterprise Rent-A-Car, Traitify and Catalyte in Baltimore along with 331 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Baltimore startup ecosystem ranks #82 globally and #28 in United States.

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Best Startups in Baltimore for 2025

SB Score:696

Enterprise Rent-A-Car is a global transportation solutions provider that offers car, truck, and motorcycle rentals as well as car sharing and car sales. Its customized rental programs are designed specifically to meet its clients’ needs. Enterprise Rent-A-Car’s mobile application allows its users to manage reservations on the go, get directions to a car rental branch, reach road side assistance 24 hours, and more. It is headquartered in Baltimore, Maryland.

Industry:
Hardware & IoT
Subindustry:
Internet of Everything

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SB Score:491

Traitify offers a visually engaging platform to apply personality assessments in a mobile-friendly format. Their embedded tool simplifies personality testing, making it accessible and easy to understand for users.

Industry:
Software & Data
Subindustry:
Software and Data-Other

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SB Score:470

Catalyte leverages data science to create tech teams for innovative companies. They specialize in software engineering services, helping businesses build future-ready workforces.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:461

Apkudo streamlines global device supply chain management, enhancing efficiencies, processes, and margins. Partner with Apkudo to engage, optimize, and improve your supply chain operations.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:448

BurnAlong offers personalized wellbeing classes and social motivation for individuals seeking health and wellness. Join a community of like-minded individuals and achieve your fitness goals with ease.

Industry:
Healthtech
Subindustry:
Fitness

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SB Score:442

Delfi Diagnostics offers highly accurate blood tests for early cancer detection, ensuring better treatment outcomes. Detecting cancer early is crucial for successful treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:440

SocialToaster enables organizations to involve their supporters in sharing content on their personal social networks. This platform simplifies the process of engaging with existing supporters and amplifying the organization's reach through social media.

Industry:
Social & Leisure
Subindustry:
Entertainment

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SB Score:440

SocialToaster is a platform that helps clients connect with and reward their social media fans. It assists in identifying, recruiting, engaging, and monetizing audiences, making fan engagement and loyalty a breeze.

Industry:
Marketing & Sales
Subindustry:
Adtech

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SB Score:434

Nest Collaborative’s comprehensive lactation support platform provides breastfeeding support by board-certified lactation consultants (IBCLCs) for parents and parents-to-be, virtually, 365 day a year. With a focus on prevention, improving access to care, and reducing care costs, Nest implements evidence-based interventions shown to extend the duration of breastfeeding for families. Preventive lactation care addresses the unique physiologic, emotional, societal, and economic barriers to breastfeeding by providing education, anticipatory guidance, reassurance, and skilled practical help and problem solving, in addition to problem based care.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:420

b.well Connected Health is a health, wellness, and fitness company that provides an integrated solution for consumer engagement, holistic health management, and cost containment. It specializes in and supports health plans, health systems, employers, and pharmaceutical companies. The platform aims to empower users to manage and optimize their healthcare experience by aggregating information from various sources, such as electronic health records, wearable devices, and other health apps.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:405

Protenus harnesses the power of AI to provide healthcare organizations with scalable risk-reduction solutions that drive the safest patient outcomes while protecting the reputation of the organizations. We are committed to innovation, determined to reduce risk, and focused on supporting our community of employees, customers, and ultimately, patients. Empowering healthcare to eliminate risk is at the heart of all we do. Founded in 2014, Protenus is a three-time winner of Forbes’ America’s Best Startup Employers, is a Great Place to Work®-Certified company, and was named one of 2021 CBInsights Digital Health 150, one of The Best Places to Work in Healthcare by Modern Healthcare, and one of the Best Places to Work in Baltimore by the Baltimore Business Journal and the Baltimore Sun. Learn more at Protenus.com and follow us on Twitter @Protenus.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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Total amount:334

Top 86 Healthtech Startups in Baltimore for 2025

The top three Healthtech startups in Baltimore have raised more than USD 542M. Baltimore startup ecosystem ranks #39 globally for the Healthtech industry.
SB Score:448

BurnAlong offers personalized wellbeing classes and social motivation for individuals seeking health and wellness. Join a community of like-minded individuals and achieve your fitness goals with ease.

Industry:
Healthtech
Subindustry:
Fitness

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SB Score:442

Delfi Diagnostics offers highly accurate blood tests for early cancer detection, ensuring better treatment outcomes. Detecting cancer early is crucial for successful treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

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b.well Connected Health is a health, wellness, and fitness company that provides an integrated solution for consumer engagement, holistic health management, and cost containment. It specializes in and supports health plans, health systems, employers, and pharmaceutical companies. The platform aims to empower users to manage and optimize their healthcare experience by aggregating information from various sources, such as electronic health records, wearable devices, and other health apps.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:86

Top 93 Software & Data Startups in Baltimore for 2025

The top three Software & Data startups in Baltimore have raised more than USD 4.43B. Baltimore startup ecosystem ranks #87 globally for the Software & Data industry.
SB Score:491

Traitify offers a visually engaging platform to apply personality assessments in a mobile-friendly format. Their embedded tool simplifies personality testing, making it accessible and easy to understand for users.

Industry:
Software & Data
Subindustry:
Software and Data-Other

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SB Score:470

Catalyte leverages data science to create tech teams for innovative companies. They specialize in software engineering services, helping businesses build future-ready workforces.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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SB Score:461

Apkudo streamlines global device supply chain management, enhancing efficiencies, processes, and margins. Partner with Apkudo to engage, optimize, and improve your supply chain operations.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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Total amount:93

Top 43 Ecommerce & Retail Startups in Baltimore for 2025

The top three Ecommerce & Retail startups in Baltimore have raised more than USD 17.2M. Baltimore startup ecosystem ranks #100 globally for the Ecommerce & Retail industry.
SB Score:322

HEX Performance offers a specialized cleaning solution for activewear and synthetic materials, ensuring they stay clean and protected. Keep your gear fresh and ready for action with HEX Performance.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

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SB Score:301

Parking Panda is the go-to platform for finding and booking parking spots. It helps parking owners maximize revenue by filling empty spaces and adjusting prices. Users can easily reserve spots online or through their mobile phones, saving time and money.

Industry:
Ecommerce & Retail
Subindustry:
Marketplaces

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SB Score:280

Fearless Sports designs and sells stylish athletic apparel for local sports enthusiasts. Their high-quality products are perfect for those looking to showcase their passion for sports with confidence and style.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce & Retail-Other

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Total amount:43

Most Funded Startups in Baltimore for 2025

The top three most funded startups in Baltimore have raised total funding of more than USD 642M. Delfi Diagnostics has 1.03% more funding than Pixelligent.
SB Score:403

EOSIO is an open-source blockchain platform designed for high performance and innovation. Supported by a passionate community, it empowers developers to create and enhance decentralized applications, fostering an environment of collaboration and growth in the blockchain space.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:442

Delfi Diagnostics offers highly accurate blood tests for early cancer detection, ensuring better treatment outcomes. Detecting cancer early is crucial for successful treatment.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:381

Producers revolutionizes composite material production by recreating a variety of natural metal oxide materials. Their innovative process provides a sustainable and efficient solution for creating high-quality composites.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

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Total amount:334

Top Hiring Startups in Baltimore by Employee Number

The top three hiring startups in Baltimore have an median employee size that is between [251-500]
SB Score:696

Enterprise Rent-A-Car is a global transportation solutions provider that offers car, truck, and motorcycle rentals as well as car sharing and car sales. Its customized rental programs are designed specifically to meet its clients’ needs. Enterprise Rent-A-Car’s mobile application allows its users to manage reservations on the go, get directions to a car rental branch, reach road side assistance 24 hours, and more. It is headquartered in Baltimore, Maryland.

Industry:
Hardware & IoT
Subindustry:
Internet of Everything

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SB Score:368

Videology is a digital media advertising technology solutions provider, providing its clients with solutions to connect advertiser brands with consumers who are most interested in those brands. By leveraging the power of consumer data and ad decisioning, we increase accountability, and optimize the performance of video and display advertising campaigns by providing a more relevant, meaningful web experience for consumers who view the ads delivered through our advertising technology solutions.

Industry:
Marketing & Sales
Subindustry:
Adtech

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SB Score:295

Oasis Group Holdings, Inc. offers an online platform for users to easily discover marinas and book boat slips. Find the perfect docking spot with just a few clicks.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:470

Catalyte leverages data science to create tech teams for innovative companies. They specialize in software engineering services, helping businesses build future-ready workforces.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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Total amount:334

Explore the Startup Ecosystem of Baltimore

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Regional Rank

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32nd

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Global Rank

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Top Cities for Startups in United States - Ranked by StartupBlink

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Quantity Score
Quality ScoreBusiness Score
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1st
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710.966
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251.377
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121.937
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00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
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