35 Top startups in Aliso Viejo for January 2025

We rank Vertos Medical, indie Semiconductor and Syxsense in Aliso Viejo along with 32 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Aliso Viejo is part of Los Angeles Area which ranks #4 globally and #3 in North America.

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Best Startups in Aliso Viejo for 2025

SB Score:517

Vertos Medical develops and sells innovative medical devices for treating spinal conditions. Their products are designed to address common spinal diseases, providing patients with effective treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:490

Indie is a tech company at the forefront of the autotech revolution, specializing in cutting-edge automotive semiconductors and software platforms.

Industry:
Transportation
Subindustry:
Automotive

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SB Score:391

This innovative IT management and security solution seamlessly integrates Vulnerability Scanning, Patch Management, and EDR functionalities. Users can easily identify and address security vulnerabilities, manage patches effectively, and enhance endpoint security all in one platform.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:387

Corent Technology offers SurPaaS, a platform for SaaS transformation and software delivery. Ideal for various companies, it streamlines processes and enhances efficiency.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:387

OrthAlign offers innovative medical devices for joint replacement patients, improving their quality of life with less pain.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:385

Spyglass Pharma is dedicated to developing innovative treatments for chronic eye diseases using advanced technology. The company aims to deliver a range of drugs targeting various ophthalmic conditions, striving to improve patient outcomes and enhance vision care.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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SB Score:363

Bright Uro develops cutting-edge diagnostic devices for Urology, combining advanced technology to provide clinicians with actionable insights. By leveraging hardware, software, and data science, they unlock new data streams to improve patient care.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:350

ThinkIQ offers a cloud-based supply chain management software for manufacturers. Streamlining operations, it enhances efficiency and transparency.

Industry:
Hardware & IoT
Subindustry:
Hardware

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SB Score:337

AWM Smart Shelf transforms the in-store shopping experience by seamlessly integrating online capabilities. It empowers retailers to enhance customer engagement, streamline inventory management, and provide personalized promotions, ultimately driving sales and improving customer satisfaction in physical marketplaces.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

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10th

vWise
SB Score:313

vWise offers a range of financial products and services tailored for financial services organizations. Their solutions are designed to help organizations effectively manage their finances and improve their overall financial performance.

Industry:
Fintech
Subindustry:
Financial Services

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SB Score:297

Okami Medical creates innovative devices to treat heart disease, improving patient outcomes. Their cutting-edge technology is revolutionizing the field with effective solutions for cardiac care.

Industry:
Healthtech
Subindustry:
Health Care

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Total amount:35

Top 12 Software & Data Startups in Aliso Viejo for 2025

The top three Software & Data startups in Aliso Viejo have raised more than USD 147M. Aliso Viejo is part of Los Angeles Area which ranks #6 globally for the Software & Data industry.
SB Score:391

This innovative IT management and security solution seamlessly integrates Vulnerability Scanning, Patch Management, and EDR functionalities. Users can easily identify and address security vulnerabilities, manage patches effectively, and enhance endpoint security all in one platform.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:387

Corent Technology offers SurPaaS, a platform for SaaS transformation and software delivery. Ideal for various companies, it streamlines processes and enhances efficiency.

Industry:
Software & Data
Subindustry:
Cloud

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SB Score:385

Spyglass Pharma is dedicated to developing innovative treatments for chronic eye diseases using advanced technology. The company aims to deliver a range of drugs targeting various ophthalmic conditions, striving to improve patient outcomes and enhance vision care.

Industry:
Software & Data
Subindustry:
Enterprise Technology

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Total amount:12

Top 3 Ecommerce & Retail Startups in Aliso Viejo for 2025

The top three Ecommerce & Retail startups in Aliso Viejo have raised more than USD 550K. Aliso Viejo is part of Los Angeles Area which ranks #3 globally for the Ecommerce & Retail industry.
SB Score:200

Visional is a cutting-edge platform and app that lets users explore and purchase products through livestream video. Discover and shop for your favorite items in real-time with ease.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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SB Score:56

Leadific is an innovative automation software that simplifies marketing processes by integrating essential systems. It empowers clients to streamline their operations, enabling them to focus on generating revenue through effective client acquisition without the burden of managing multiple platforms.

Industry:
Ecommerce & Retail
Subindustry:
Social Commerce

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Total amount:3

Top 1 Social & Leisure Startups in Aliso Viejo for 2025

Aliso Viejo is part of Los Angeles Area which ranks #4 globally for the Social & Leisure industry.
SB Score:144

A premier music platform for independent artists and labels to showcase, promote, and earn from their content. Boost exposure and monetize your talent in the global music community.

Industry:
Social & Leisure
Subindustry:
Entertainment

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Total amount:1

Most Funded Startups in Aliso Viejo for 2025

The top three most funded startups in Aliso Viejo have raised total funding of more than USD 345M. Vertos Medical has 0.58% more funding than Spyglass Pharma.
SB Score:517

Vertos Medical develops and sells innovative medical devices for treating spinal conditions. Their products are designed to address common spinal diseases, providing patients with effective treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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SB Score:385

Spyglass Pharma is dedicated to developing innovative treatments for chronic eye diseases using advanced technology. The company aims to deliver a range of drugs targeting various ophthalmic conditions, striving to improve patient outcomes and enhance vision care.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Regional Rank (North America)

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SB Score:363

Bright Uro develops cutting-edge diagnostic devices for Urology, combining advanced technology to provide clinicians with actionable insights. By leveraging hardware, software, and data science, they unlock new data streams to improve patient care.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

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Total amount:35

Top Hiring Startups in Aliso Viejo by Employee Number

The top three hiring startups in Aliso Viejo have an median employee size that is between [501-1000]
SB Score:490

Indie is a tech company at the forefront of the autotech revolution, specializing in cutting-edge automotive semiconductors and software platforms.

Industry:
Transportation
Subindustry:
Automotive

National Rank (United States)

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SB Score:246

CyberProof efficiently handles security operations, reducing response time and costs while minimizing business risk.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

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SB Score:391

This innovative IT management and security solution seamlessly integrates Vulnerability Scanning, Patch Management, and EDR functionalities. Users can easily identify and address security vulnerabilities, manage patches effectively, and enhance endpoint security all in one platform.

Industry:
Software & Data
Subindustry:
Cloud

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

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SB Score:517

Vertos Medical develops and sells innovative medical devices for treating spinal conditions. Their products are designed to address common spinal diseases, providing patients with effective treatment options.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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Total amount:35

Explore the Startup Ecosystem of Aliso Viejo

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Quality ScoreBusiness Score
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710.966
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251.377
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121.937
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109.679
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