Top Unicorn Startups in Houston for 2025

In Houston, we rank 4 unicorn startups based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Unicorns in Houston are falling behind the performance of their global counterparts.

Powered by:

Top Unicorn Startups in Houston for 2025

SB Score:667

HighRadius is a Fintech SaaS company using AI to automate Accounts Receivable and Treasury processes for businesses.

Industry:
Fintech
Subindustry:
Marketplaces

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:593

Axiom Space offers commercial human spaceflight services, providing access to the ISS now and the upcoming Axiom Station in 2024. Leading the industry, they enable individuals to experience space travel firsthand.

Industry:
Transportation
Subindustry:
Aerospace

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:499

Solugen is a biotech startup that transforms plant-based materials into high-quality chemicals using its unique hydrogen peroxide technology, developed by a team of MIT experts. This innovative approach distinguishes Solugen in the industry, promoting sustainable practices while delivering exceptional chemical products.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:4

Best Healthtech Startups in Houston for 2025

Houston startups in the Healthtech industry are underperforming their global industry peers. The top three Healthtech unicorns in Houston have raised more than USD 318M, an amount that is lower than the global industry average.
SB Score:499

Solugen is a biotech startup that transforms plant-based materials into high-quality chemicals using its unique hydrogen peroxide technology, developed by a team of MIT experts. This innovative approach distinguishes Solugen in the industry, promoting sustainable practices while delivering exceptional chemical products.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:1

Most Valuable Unicorns in Houston for 2025

The top three most valuable unicorns in Houston have raised total funding of more than USD 900M. Among the top three funded unicorns, the most popular industry, based on total funding, is Healthtech.
SB Score:667

HighRadius is a Fintech SaaS company using AI to automate Accounts Receivable and Treasury processes for businesses.

Industry:
Fintech
Subindustry:
Marketplaces

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:499

Solugen is a biotech startup that transforms plant-based materials into high-quality chemicals using its unique hydrogen peroxide technology, developed by a team of MIT experts. This innovative approach distinguishes Solugen in the industry, promoting sustainable practices while delivering exceptional chemical products.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:72

Mercury, managing over $500 million and generating $8 billion in value since its inception, specializes in supporting entrepreneurs and startups throughout Middle America. The firm is dedicated to empowering innovative businesses, fostering growth, and driving success in the region’s vibrant entrepreneurial landscape.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:593

Axiom Space offers commercial human spaceflight services, providing access to the ISS now and the upcoming Axiom Station in 2024. Leading the industry, they enable individuals to experience space travel firsthand.

Industry:
Transportation
Subindustry:
Aerospace

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:4

Top Hiring Unicorns in Houston by Employee Number

The top three hiring unicorns in Houston have an average employee size that is smaller than to the global average. Among these, the Fintech industry features the unicorn with the largest workforce.
SB Score:667

HighRadius is a Fintech SaaS company using AI to automate Accounts Receivable and Treasury processes for businesses.

Industry:
Fintech
Subindustry:
Marketplaces

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:593

Axiom Space offers commercial human spaceflight services, providing access to the ISS now and the upcoming Axiom Station in 2024. Leading the industry, they enable individuals to experience space travel firsthand.

Industry:
Transportation
Subindustry:
Aerospace

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:499

Solugen is a biotech startup that transforms plant-based materials into high-quality chemicals using its unique hydrogen peroxide technology, developed by a team of MIT experts. This innovative approach distinguishes Solugen in the industry, promoting sustainable practices while delivering exceptional chemical products.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:72

Mercury, managing over $500 million and generating $8 billion in value since its inception, specializes in supporting entrepreneurs and startups throughout Middle America. The firm is dedicated to empowering innovative businesses, fostering growth, and driving success in the region’s vibrant entrepreneurial landscape.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:4

Explore the Startup Ecosystem of Houston

National Rank

(undefined)

19th

0

Regional Rank

(undefined)

22nd

0

Global Rank

(WorldWide)

48th

4

Visit
Top Cities for Startups in United States - Ranked by StartupBlink
StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
Pro
2024 National Rank CityGlobal RankTotal Score

Access subscores for 1000 cities and 100 countries

Quantity Score
Quality ScoreBusiness Score
1st
0
1st
0
710.966
00.00
00.00
00.00
2nd
0
2nd
0
251.377
00.00
00.00
00.00
3rd
0
4th
0
121.937
00.00
00.00
00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
Microsoft Excel icon
Download CSV file
Pro