Top Unicorn Startups in Cambridge for 2025

In Cambridge, we rank 9 unicorn startups based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Unicorns in Cambridge are falling behind the performance of their global counterparts.

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Top Unicorn Startups in Cambridge for 2025

SB Score:647

Formlabs pioneers affordable, high-resolution desktop 3D printing with the Form 1. This MIT-spawned team thrives on curiosity and innovation to create tools that revolutionize work and life. Join us for a future-changing adventure at http://formlabs.com/jobs.

Industry:
Software & Data
Subindustry:
Software and Data-Other

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SB Score:565

Scroll is a news venture firm providing services for journalists. They offer a platform that streamlines the news reading experience by removing ads and distractions, allowing journalists to focus on quality reporting.

Industry:
Social & Leisure
Subindustry:
Digital Media

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SB Score:516

Solo.io creates tools for enterprises to optimize cloud technologies, enabling seamless adaptation and innovation. Their solutions empower businesses to maximize the benefits of cutting-edge cloud services.

Industry:
Software & Data
Subindustry:
Apps

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Total amount:9

Best Healthtech Startups in Cambridge for 2025

Cambridge startups in the Healthtech industry are overperforming their global industry peers. The top three Healthtech unicorns in Cambridge have raised more than USD 2.27B, an amount that is higher than the global industry average.
SB Score:497

Tessera Therapeutics is an innovative biotech company developing cutting-edge therapeutics. They aim to revolutionize healthcare by harnessing the power of genetic engineering to create groundbreaking treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:458

Orna Therapeutics creates innovative circular RNA therapeutics to revolutionize disease treatment. Their fully engineered oRNAs offer a new approach to therapy, with the potential to transform healthcare.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

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Total amount:2

Most Valuable Unicorns in Cambridge for 2025

The top three most valuable unicorns in Cambridge have raised total funding of more than USD 3.37B. Among the top three funded unicorns, the most popular industry, based on total funding, is Software & Data.
SB Score:647

Formlabs pioneers affordable, high-resolution desktop 3D printing with the Form 1. This MIT-spawned team thrives on curiosity and innovation to create tools that revolutionize work and life. Join us for a future-changing adventure at http://formlabs.com/jobs.

Industry:
Software & Data
Subindustry:
Software and Data-Other

National Rank (United States)

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Regional Rank (North America)

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2nd

Hive
SB Score:24

This startup utilizes gene sequencing and CRISPR/Cas9 technologies for precise and affordable genome mapping and editing. The focus is on accelerating the understanding of human disease mechanisms and developing breakthrough therapies by automating manual experimentation processes.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (United States)

0

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Regional Rank (North America)

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SB Score:565

Scroll is a news venture firm providing services for journalists. They offer a platform that streamlines the news reading experience by removing ads and distractions, allowing journalists to focus on quality reporting.

Industry:
Social & Leisure
Subindustry:
Digital Media

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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SB Score:497

Tessera Therapeutics is an innovative biotech company developing cutting-edge therapeutics. They aim to revolutionize healthcare by harnessing the power of genetic engineering to create groundbreaking treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:487

Inari revolutionizes the agricultural sector, benefiting farmers, buyers, and the planet with groundbreaking innovations.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

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Regional Rank (North America)

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SB Score:458

Orna Therapeutics creates innovative circular RNA therapeutics to revolutionize disease treatment. Their fully engineered oRNAs offer a new approach to therapy, with the potential to transform healthcare.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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Cambridge Mobile Telematics is a top provider of telematics and analytics for insurers, rideshares, and fleets. Their innovative technology helps improve driving behavior and safety.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

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Global Rank (WorldWide)

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SB Score:516

Solo.io creates tools for enterprises to optimize cloud technologies, enabling seamless adaptation and innovation. Their solutions empower businesses to maximize the benefits of cutting-edge cloud services.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

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Regional Rank (North America)

0

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Global Rank (WorldWide)

0

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Total amount:9

Top Hiring Unicorns in Cambridge by Employee Number

The top three hiring unicorns in Cambridge have an average employee size that is smaller than to the global average. Among these, the Software & Data industry features the unicorn with the largest workforce.
SB Score:647

Formlabs pioneers affordable, high-resolution desktop 3D printing with the Form 1. This MIT-spawned team thrives on curiosity and innovation to create tools that revolutionize work and life. Join us for a future-changing adventure at http://formlabs.com/jobs.

Industry:
Software & Data
Subindustry:
Software and Data-Other

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:497

Tessera Therapeutics is an innovative biotech company developing cutting-edge therapeutics. They aim to revolutionize healthcare by harnessing the power of genetic engineering to create groundbreaking treatments.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:487

Inari revolutionizes the agricultural sector, benefiting farmers, buyers, and the planet with groundbreaking innovations.

Industry:
Foodtech
Subindustry:
Agtech

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Cambridge Mobile Telematics is a top provider of telematics and analytics for insurers, rideshares, and fleets. Their innovative technology helps improve driving behavior and safety.

Industry:
Software & Data
Subindustry:
Apps

National Rank (United States)

0

View

Regional Rank (North America)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:9

Explore the Startup Ecosystem of Cambridge

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Quantity Score
Quality ScoreBusiness Score
1st
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1st
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710.966
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2nd
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2nd
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251.377
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3rd
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4th
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121.937
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4th
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5th
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109.679
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