64 Top startups in Seville for April 2025

We rank Wuolah, CoverManager and CheKin in Seville along with 61 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Seville startup ecosystem ranks #354 globally and #6 in Spain.

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Best Startups in Seville for 2025

SB Score:522

Wuolah is a platform where university students can earn money and recognition by sharing their course notes. Users can upload their notes in exchange for a financial reward and gain prestige within the student community.

Industry:
Ecommerce & Retail
Subindustry:
Social Commerce

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SB Score:508

CoverManager is an innovative tool designed for restaurants, enabling them to effortlessly create, sell, and manage reservations. With its user-friendly interface, it streamlines the reservation process, enhances customer experiences, and optimizes operational efficiency, making it an essential solution for restaurant owners.

Industry:
Foodtech
Subindustry:
Food and Beverage

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SB Score:483

Chekin has created a comprehensive framework that streamlines guest registration for tourist accommodations. It simplifies the process for third-party software providers, including startups and travel companies, enabling them to efficiently register guests and enhance their operational capabilities with ease.

Industry:
Software & Data
Subindustry:
Apps

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SB Score:400

Lico Cosmetics is a pioneering chemical engineering company dedicated to formulating high-end cosmetics. Backed by women entrepreneurs and industry specialists, it champions eco-friendly beauty solutions, merging innovation with a passion for sustainable practices in the cosmetics sector.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

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SB Score:376

Tutrocito is an online store that offers a wide range of decorative supplies and custom-made furniture. With a focus on quality and creativity, it empowers customers to elevate their spaces with unique designs tailored to their individual tastes and preferences.

Industry:
Ecommerce & Retail
Subindustry:
Consumer Goods

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SB Score:362

Universal Diagnostics S.L. (UDX) is a Spanish in-vitro diagnostics company developing a platform of minimally-invasive, blood-based solutions for detecting cancer early when treatment options are more plentiful and survival rates are still high. UDX believes that the best way to fight against cancer is by detecting it early. The UDX diagnostic platform is designed to detect various cancer types, e.g. colorectal, liver, pancreatic, lung, and gastric cancer via one simple blood test. The assays rely on a curated set of proprietary methylation marker panels, a simple blood sample collected as part of a routine check-up, can be processed at a reference laboratory or hospital using standard equipment and then uploaded to the UDX Cloud for final algorithmic analysis. UDX’s first marker panel is a colorectal cancer screening test. The test identifies individuals who need to be referred for colonoscopy. Colorectal cancer is the 3rd most frequent cancer and 2nd deadliest cancer worldwide. The challenge is that colorectal cancer is mostly detected in late stages, with significantly decreased survival rates (11% survival rate in stage IV vs. 85% survival rate in stage I). To develop the test and execute its R&D and operations, UDX partners with international research institutions, hospitals, universities, and biobanks around the globe.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:353

AdWALK is an innovative augmented reality platform that utilizes artificial intelligence and computer vision to provide users with hands-free, device-less experiences. By analyzing users' movements and gestures, AdWALK creates immersive augmented reality environments without the need for glasses or phones.

Industry:
Software & Data
Subindustry:
SaaS

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8th

Mox
SB Score:351

Mox optimizes production capacity with efficient logistics services. Maximize your potential with Mox's streamlined solutions.

Industry:
Foodtech
Subindustry:
Food and Beverage

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SB Score:346

OpenWebinars is a cutting-edge eLearning platform for all things tech. Offering engaging courses, it empowers users to enhance their skills and knowledge. Join us to unlock your potential in the digital world.

Industry:
Edtech
Subindustry:
Edtech

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SB Score:342

MYHIXEL offers a scientifically backed solution for male sexual well-being, combining medical expertise with innovative technology. This platform empowers men to enhance their sexual health through personalized training and support, promoting confidence and satisfaction in their intimate lives.

Industry:
Social & Leisure
Subindustry:
Communities

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11th

Zinkee
SB Score:327

Zinkee is a technology-driven firm that creates and implements business management tools aimed at fostering company growth. By offering innovative solutions, they empower businesses to optimize operations, improve efficiency, and achieve their strategic objectives.

Industry:
Software & Data
Subindustry:
Apps

National Rank (Spain)

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Total amount:64

Top 20 Software & Data Startups in Seville for 2025

The top three Software & Data startups in Seville have raised more than USD 7.61M. Seville startup ecosystem ranks #358 globally for the Software & Data industry.
SB Score:483

Chekin has created a comprehensive framework that streamlines guest registration for tourist accommodations. It simplifies the process for third-party software providers, including startups and travel companies, enabling them to efficiently register guests and enhance their operational capabilities with ease.

Industry:
Software & Data
Subindustry:
Apps

National Rank (Spain)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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SB Score:353

AdWALK is an innovative augmented reality platform that utilizes artificial intelligence and computer vision to provide users with hands-free, device-less experiences. By analyzing users' movements and gestures, AdWALK creates immersive augmented reality environments without the need for glasses or phones.

Industry:
Software & Data
Subindustry:
SaaS

National Rank (Spain)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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SB Score:327

Zinkee is a technology-driven firm that creates and implements business management tools aimed at fostering company growth. By offering innovative solutions, they empower businesses to optimize operations, improve efficiency, and achieve their strategic objectives.

Industry:
Software & Data
Subindustry:
Apps

National Rank (Spain)

0

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Regional Rank (Western Europe)

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Total amount:20

Top 6 Healthtech Startups in Seville for 2025

The top three Healthtech startups in Seville have raised more than USD 322M. Seville startup ecosystem ranks #244 globally for the Healthtech industry.
SB Score:362

Universal Diagnostics S.L. (UDX) is a Spanish in-vitro diagnostics company developing a platform of minimally-invasive, blood-based solutions for detecting cancer early when treatment options are more plentiful and survival rates are still high. UDX believes that the best way to fight against cancer is by detecting it early. The UDX diagnostic platform is designed to detect various cancer types, e.g. colorectal, liver, pancreatic, lung, and gastric cancer via one simple blood test. The assays rely on a curated set of proprietary methylation marker panels, a simple blood sample collected as part of a routine check-up, can be processed at a reference laboratory or hospital using standard equipment and then uploaded to the UDX Cloud for final algorithmic analysis. UDX’s first marker panel is a colorectal cancer screening test. The test identifies individuals who need to be referred for colonoscopy. Colorectal cancer is the 3rd most frequent cancer and 2nd deadliest cancer worldwide. The challenge is that colorectal cancer is mostly detected in late stages, with significantly decreased survival rates (11% survival rate in stage IV vs. 85% survival rate in stage I). To develop the test and execute its R&D and operations, UDX partners with international research institutions, hospitals, universities, and biobanks around the globe.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (Spain)

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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SB Score:312

ReHand is an innovative telerehabilitation solution designed for the wrist, hand, and fingers. It offers a user-friendly healthcare tool optimized for tablet touch screens, enabling patients to perform scientifically validated exercises at home or in the office, promoting effective recovery and rehabilitation.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (Spain)

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SB Score:295

Developing multi-valent vaccines to prevent antibiotic-resistant infections worldwide, this startup is revolutionizing healthcare with innovative solutions for a global challenge.

Industry:
Healthtech
Subindustry:
Medtech

National Rank (Spain)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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Total amount:6

Top 8 Hardware & IoT Startups in Seville for 2025

The top three Hardware & IoT startups in Seville have raised more than USD 11.6M. Seville startup ecosystem ranks #239 globally for the Hardware & IoT industry.
SB Score:303

REGEMAT3D is a leading biotech company specializing in using 3D printing for regenerative therapies. Their innovative approach revolutionizes the field by creating cutting-edge solutions for regenerating tissues.

Industry:
Hardware & IoT
Subindustry:
3D Printing

National Rank (Spain)

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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SB Score:261

Build to Zero is a climate technology company focusing on thermal energy storage solutions that enable industrial heat decarbonization. By harnessing innovative technology, it empowers industries to efficiently manage energy use, reduce carbon emissions, and transition towards a sustainable future.

Industry:
Hardware & IoT
Subindustry:
Hardware

National Rank (Spain)

0

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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SB Score:258

LiveLink Motor offers car telematics technology. They also offer API integration, ecu, can integration, app development, and software solutions in their product line. It is constantly looking for new ways to apply cutting-edge technology to areas with a social impact, with a particular focus on the creation of an emergency device for motorcyclists capable of detecting any accident that a motorcyclist may have.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (Spain)

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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Total amount:8

Most Funded Startups in Seville for 2025

The top three most funded startups in Seville have raised total funding of more than USD 375M. Universal Diagnostics has 4.18% more funding than CoverManager.
SB Score:362

Universal Diagnostics S.L. (UDX) is a Spanish in-vitro diagnostics company developing a platform of minimally-invasive, blood-based solutions for detecting cancer early when treatment options are more plentiful and survival rates are still high. UDX believes that the best way to fight against cancer is by detecting it early. The UDX diagnostic platform is designed to detect various cancer types, e.g. colorectal, liver, pancreatic, lung, and gastric cancer via one simple blood test. The assays rely on a curated set of proprietary methylation marker panels, a simple blood sample collected as part of a routine check-up, can be processed at a reference laboratory or hospital using standard equipment and then uploaded to the UDX Cloud for final algorithmic analysis. UDX’s first marker panel is a colorectal cancer screening test. The test identifies individuals who need to be referred for colonoscopy. Colorectal cancer is the 3rd most frequent cancer and 2nd deadliest cancer worldwide. The challenge is that colorectal cancer is mostly detected in late stages, with significantly decreased survival rates (11% survival rate in stage IV vs. 85% survival rate in stage I). To develop the test and execute its R&D and operations, UDX partners with international research institutions, hospitals, universities, and biobanks around the globe.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (Spain)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:508

CoverManager is an innovative tool designed for restaurants, enabling them to effortlessly create, sell, and manage reservations. With its user-friendly interface, it streamlines the reservation process, enhances customer experiences, and optimizes operational efficiency, making it an essential solution for restaurant owners.

Industry:
Foodtech
Subindustry:
Food and Beverage

National Rank (Spain)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:295

Developing multi-valent vaccines to prevent antibiotic-resistant infections worldwide, this startup is revolutionizing healthcare with innovative solutions for a global challenge.

Industry:
Healthtech
Subindustry:
Medtech

National Rank (Spain)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
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Total amount:64

Top Hiring Startups in Seville by Employee Number

The top three hiring startups in Seville have an median employee size that is between [51-100]

1st

Mox
SB Score:351

Mox optimizes production capacity with efficient logistics services. Maximize your potential with Mox's streamlined solutions.

Industry:
Foodtech
Subindustry:
Food and Beverage

National Rank (Spain)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
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SB Score:522

Wuolah is a platform where university students can earn money and recognition by sharing their course notes. Users can upload their notes in exchange for a financial reward and gain prestige within the student community.

Industry:
Ecommerce & Retail
Subindustry:
Social Commerce

National Rank (Spain)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:483

Chekin has created a comprehensive framework that streamlines guest registration for tourist accommodations. It simplifies the process for third-party software providers, including startups and travel companies, enabling them to efficiently register guests and enhance their operational capabilities with ease.

Industry:
Software & Data
Subindustry:
Apps

National Rank (Spain)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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SB Score:106

Z1 Digital Studio transforms ideas into digital products with a focus on scalability, viability, and desirability. Their approach ensures a balanced understanding of all aspects, resulting in amazing products that meet true needs.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (Spain)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

0

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Total amount:64

Explore the Startup Ecosystem of Seville

National Rank

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Regional Rank

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109th

5

Global Rank

(WorldWide)

354th

22

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Top Cities for Startups in Spain - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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