36 Top startups in Leiden for April 2025

We rank ChannelEngine, Ncardia and Vico Therapeutics in Leiden along with 33 other startups based on an algorithm that scores startups based on total investment, employee count, and quarterly website traffic. Leiden is part of The Hague startup ecosystem which ranks #138 globally and #34 in Western Europe.

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Best Startups in Leiden for 2025

SB Score:483

ChannelEngine streamlines marketplace selling for brands, wholesalers, and retailers through automated processes. Maximize sales potential effortlessly with our platform.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (The Netherlands)

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SB Score:438

Ncardia accelerates drug discovery with innovative biotechnology solutions. Their platform streamlines development processes for pharmaceutical companies, making research faster and more efficient.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:428

Vico Therapeutics develops RNA modulating therapies to treat genetic diseases. Their innovative approach aims to harness the power of RNA to target and correct specific genetic abnormalities, offering new hope for patients in need of effective treatments.

Industry:
Healthtech
Subindustry:
Health Care

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SB Score:428

In Ovo revolutionizes the poultry industry with biotechnological solutions that prioritize animal welfare and efficiency. Their innovative approach enhances the industry by combining cutting-edge technology with a focus on ethical practices.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:424

Samotics offers a cutting-edge predictive maintenance solution for AC motors and rotating equipment. Boost efficiency and reduce downtime with advanced monitoring and analysis tailored to your specific needs. Say goodbye to unexpected breakdowns and hello to optimized performance.

Industry:
Hardware & IoT
Subindustry:
Internet of Everything

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SB Score:413

Campspace connects outdoor enthusiasts with private landowners, providing unique opportunities for people to escape the daily grind and reconnect with nature. Hosts can share their outdoor space with conscious travelers, creating memorable experiences for all.

Industry:
Social & Leisure
Subindustry:
Travel

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SB Score:402

MIMETAS creates organ-on-a-chip models for precise and personalized drug development. Their innovative technology improves the accuracy and effectiveness of medicine testing.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:366

Azafaros develops innovative treatments for rare metabolic disorders. Their goal is to create new therapeutic agents that improve the lives of patients in need.

Industry:
Healthtech
Subindustry:
Biotechnology

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SB Score:334

ISA Pharmaceuticals develops synthetic therapeutic vaccines for cancer treatment, offering innovative solutions to combat the disease.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (The Netherlands)

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Regional Rank (Western Europe)

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Total amount:36

Top 3 Software & Data Startups in Leiden for 2025

The top three Software & Data startups in Leiden have raised more than USD 72.8M. Leiden is part of The Hague startup ecosystem which ranks #130 globally for the Software & Data industry.
SB Score:483

ChannelEngine streamlines marketplace selling for brands, wholesalers, and retailers through automated processes. Maximize sales potential effortlessly with our platform.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (The Netherlands)

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Regional Rank (Western Europe)

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SB Score:251

This innovative startup empowers the 300 million people worldwide who struggle with voice disabilities or severe stuttering. By enhancing communication capabilities, it enables users to make clear and relaxed phone and video calls, improving their daily interactions, work life, and overall well-being.

Industry:
Software & Data
Subindustry:
Apps

National Rank (The Netherlands)

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Regional Rank (Western Europe)

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SB Score:56

DAISYS is at the forefront of voice AI innovation, utilizing a unique disentanglement architecture to develop highly customizable and emotionally expressive AI voices. This groundbreaking approach transcends the limitations of traditional one-size-fits-all solutions, enabling users to create tailored voice experiences that resonate deeply with their audiences.

Industry:
Software & Data
Subindustry:
Artificial Intelligence

National Rank (The Netherlands)

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Regional Rank (Western Europe)

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Total amount:3

Top 24 Healthtech Startups in Leiden for 2025

The top three Healthtech startups in Leiden have raised more than USD 423M. Leiden is part of The Hague startup ecosystem which ranks #95 globally for the Healthtech industry.
SB Score:438

Ncardia accelerates drug discovery with innovative biotechnology solutions. Their platform streamlines development processes for pharmaceutical companies, making research faster and more efficient.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (The Netherlands)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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SB Score:428

Vico Therapeutics develops RNA modulating therapies to treat genetic diseases. Their innovative approach aims to harness the power of RNA to target and correct specific genetic abnormalities, offering new hope for patients in need of effective treatments.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (The Netherlands)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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SB Score:428

In Ovo revolutionizes the poultry industry with biotechnological solutions that prioritize animal welfare and efficiency. Their innovative approach enhances the industry by combining cutting-edge technology with a focus on ethical practices.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (The Netherlands)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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Total amount:24

Top 3 Hardware & IoT Startups in Leiden for 2025

The top three Hardware & IoT startups in Leiden have raised more than USD 67.7M. Leiden is part of The Hague startup ecosystem which ranks #80 globally for the Hardware & IoT industry.
SB Score:424

Samotics offers a cutting-edge predictive maintenance solution for AC motors and rotating equipment. Boost efficiency and reduce downtime with advanced monitoring and analysis tailored to your specific needs. Say goodbye to unexpected breakdowns and hello to optimized performance.

Industry:
Hardware & IoT
Subindustry:
Internet of Everything

National Rank (The Netherlands)

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Regional Rank (Western Europe)

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SB Score:207

KRUSH Brands is an innovative food technology company that operates a multi-kitchen food service, delivering delicious meals to customers. With a portfolio that includes Freedom Pizza, Wildflower Poke & More, Coco Yogo Vegan Kitchen, and the Salad Jar, along with partnerships with Viking Bageri and Jetlagged Chef, KRUSH Brands redefines dining convenience.

Industry:
Hardware & IoT
Subindustry:
Manufacturing

National Rank (The Netherlands)

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Regional Rank (Western Europe)

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Total amount:3

Most Funded Startups in Leiden for 2025

The top three most funded startups in Leiden have raised total funding of more than USD 423M. Vico Therapeutics has 0.54% more funding than VarmX.
SB Score:428

Vico Therapeutics develops RNA modulating therapies to treat genetic diseases. Their innovative approach aims to harness the power of RNA to target and correct specific genetic abnormalities, offering new hope for patients in need of effective treatments.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (The Netherlands)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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SB Score:327

VarmX B.V. produces therapeutic proteins that quickly repair blood clotting in patients experiencing bleeding.

Industry:
Healthtech
Subindustry:
Pharmaceuticals

National Rank (The Netherlands)

0

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Regional Rank (Western Europe)

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Global Rank (WorldWide)

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SB Score:428

In Ovo revolutionizes the poultry industry with biotechnological solutions that prioritize animal welfare and efficiency. Their innovative approach enhances the industry by combining cutting-edge technology with a focus on ethical practices.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (The Netherlands)

0

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Regional Rank (Western Europe)

0

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Global Rank (WorldWide)

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Total amount:36

Top Hiring Startups in Leiden by Employee Number

The top three hiring startups in Leiden have an median employee size that is between [101-250]
SB Score:483

ChannelEngine streamlines marketplace selling for brands, wholesalers, and retailers through automated processes. Maximize sales potential effortlessly with our platform.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (The Netherlands)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:424

Samotics offers a cutting-edge predictive maintenance solution for AC motors and rotating equipment. Boost efficiency and reduce downtime with advanced monitoring and analysis tailored to your specific needs. Say goodbye to unexpected breakdowns and hello to optimized performance.

Industry:
Hardware & IoT
Subindustry:
Internet of Everything

National Rank (The Netherlands)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page
SB Score:402

MIMETAS creates organ-on-a-chip models for precise and personalized drug development. Their innovative technology improves the accuracy and effectiveness of medicine testing.

Industry:
Healthtech
Subindustry:
Biotechnology

National Rank (The Netherlands)

0

View

Regional Rank (Western Europe)

0

View

Global Rank (WorldWide)

0

Browse
View full page

Total amount:36

Explore the Startup Ecosystem of Leiden

National Rank

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3rd

1

Regional Rank

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34th

2

Global Rank

(WorldWide)

138th

1

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Top Cities for Startups in The Netherlands - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal Rank
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Total Score

Access subscores for 1000 cities and 100 countries

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Quantity Score
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Quality Score
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Business Score
1st
0
28th
-
1
29.673
00.00
00.00
00.00
2nd
+
1
104th
+
59
7.344
00.00
00.00
00.00
3rd
-
1
138th
+
1
5.036
00.00
00.00
00.00
4th
0
166th
+
13
3.790
00.00
00.00
00.00
5th
0
182nd
+
11
3.129
00.00
00.00
00.00
6th
0
257th
-
29
1.632
00.00
00.00
00.00
7th
0
308th
-
37
1.248
00.00
00.00
00.00
8th
+
1
415th
+
159
0.748
00.00
00.00
00.00
9th
-
1
487th
-
33
0.518
00.00
00.00
00.00
10th
+
4
535th
+
190
0.418
00.00
00.00
00.00
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