Top Startup Exits in Boston for 2025

In Boston, we rank 39 startup exits based on an algorithm that considers factors such as total investment, quarterly employee count, and website traffic. Startup exits in Boston are falling behind the performance of their global counterparts.

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Top Startup Exits in Boston for 2025

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StudentUniverse is a technology company that provides students with exclusive deals. We've built our own search, booking and verification tech. We're basically a bunch of geeks and business people that run the most visited student deals site in the U.S. By verifying student status we are able to offer students access to exclusive deals and experiences. We connect with a large network of engaged members and millions of students visit StudentUniverse every year.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Unranked

Circulation uses cutting-edge technology to manage the logistics and transportation throughout healthcare. It drives efficiency and better outcomes of populations throughout the U.S.

Industry:
Healthtech
Subindustry:
Health Care

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Pyxis Oncology is a developer of antibody therapeutics intended to promote the body's immune response to cancer. The company has engaged in deep analyses of tumor antigen-specific tumor-infiltrating lymphocytes (TILs) within hot tumors and of tumor cell signaling pathways within cold tumors, providing laboratories with development of novel antibody-based immunotherapies. It was founded in 2019 and is based in Boston, Massachusetts.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:39

Best Healthtech Startup Exits in Boston for 2025

Boston exits in the Healthtech industry are overperforming their global industry peers. The top three Healthtech exits in Boston have raised more than USD 1.84B, an amount that is higher than the global industry average.
Unranked

Circulation uses cutting-edge technology to manage the logistics and transportation throughout healthcare. It drives efficiency and better outcomes of populations throughout the U.S.

Industry:
Healthtech
Subindustry:
Health Care

National Rank (United States)

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Pyxis Oncology is a developer of antibody therapeutics intended to promote the body's immune response to cancer. The company has engaged in deep analyses of tumor antigen-specific tumor-infiltrating lymphocytes (TILs) within hot tumors and of tumor cell signaling pathways within cold tumors, providing laboratories with development of novel antibody-based immunotherapies. It was founded in 2019 and is based in Boston, Massachusetts.

Industry:
Healthtech
Subindustry:
Biotechnology

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Unranked

Invetx is a veterinary therapeutics company that develops protein-based therapeutics for animal health. Invetx's network includes animal and human health experts, veterinary scientists, and clinicians.

Industry:
Healthtech
Subindustry:
Biotechnology

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Total amount:15

Largest Startup Exits in Boston by Funding

The top three largest startup exits in Boston have raised total funding of more than USD 288M. Among the top three funded exits, the most popular industry, based on total funding, is Software & Data.
Unranked

Klaviyo is an email marketing platform created for online businesses — featuring powerful email and SMS marketing automation.

Industry:
Software & Data
Subindustry:
Software

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DraftKings is a sports oriented skill gaming company based in Boston, MA. Our core products are currently in the short-format Fantasy Sports space: DraftKings.com, the leading Daily Fantasy Sports for Cash site, and Fantasy Sports for Coins, a top rated fantasy sports app with versions for the iPhone, Android and Facebook Canvas.

Industry:
Social & Leisure
Subindustry:
Gaming

National Rank (United States)

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Total amount:39

Top Hiring Startup Exits in Boston by Employee Size

The top three hiring startup exits in Boston have an average employee size that is smaller than to the global average. Among these, the Ecommerce & Retail industry features the startup exit with the largest workforce.
Unranked

Wayfair is an online retailer of home products for bedroom, living room, kitchen and dining, home entertainment, bathroom, and more.

Industry:
Ecommerce & Retail
Subindustry:
Ecommerce

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Unranked

Acquia specializes in providing cloud-based digital experience management solutions.

Industry:
Hardware & IoT
Subindustry:
Consumer Electronics

National Rank (United States)

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Unranked

Amwell is a telehealth platform in the United States and globally, connecting and enabling providers, insurers, patients, and innovators to deliver greater access to more affordable, higher quality care. Amwell believes that digital care delivery will transform healthcare. The company offers a single, comprehensive platform to support all telehealth needs from urgent to acute and post-acute care, as well as chronic care management and healthy living. With over a decade of experience, Amwell powers telehealth solutions for over 240 health systems comprised of 2,000 hospitals and 55 health plan partners with over 36,000 employers, reaching over 150 million lives. Amwell was founded in 2006 and is headquartered in Boston, Massachusetts.

Industry:
Software & Data
Subindustry:
Enterprise Technology

National Rank (United States)

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Total amount:39

Explore the Startup Ecosystem of Boston

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Top Cities for Startups in United States - Ranked by StartupBlink

StartupBlink ranks the startup ecosystems of more than 100 countries and 1,000 cities. Download our latest Global Startup Ecosystem Report.
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2024 National Rank CityGlobal RankTotal Score

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Quantity Score
Quality ScoreBusiness Score
1st
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1st
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710.966
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2nd
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2nd
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251.377
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3rd
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4th
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121.937
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00.00
4th
0
5th
0
109.679
00.00
00.00
00.00
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